Advertisement

Czechoslovak Journal of Physics

, Volume 53, Supplement 1, pp A763–A768 | Cite as

Cyclotron produced radiopharmaceuticals

  • K. Kopička
  • M. Fišer
  • P. Hradilek
  • P. Hanč
  • O. Lebeda
Part II Session 8: Nuclear Methods in Medicine, Radiopharmaceuticals and Radiodiagnostics, Labelled Compounds
  • 76 Downloads

Abstract

Some of the cyclotron-produced radionuclides may serve as important materials for the production of radiopharmaceuticals. This lecture deals with basic information relating to various aspects of these compounds. In comparison with radionuclides/compounds used for non-medical purposes, radiopharmaceuticals are subject to a broader scale of regulations, both from the safety and efficacy point of view; besides that, there are both radioactive and medical aspects that must be taken into account for any radiopharmaceutical. According to the regulations and in compliance with general rules of work with radioactivity, radiopharmaceuticals should only be prepared/manufactured under special conditions, using special areas and special equipment and applying special procedures (e.g. sterilisation, disinfection, aseptic work). Also, there are special procedures for cleaning and maintenance. Sometimes the requirements for the product safety clash with those for the safety of the personnel; several examples of solutions pertaining to these cases are given in the lecture. Also, the specific role of cyclotron radiopharmaceuticals is discussed.

Keywords

Radionuclide Special Procedure Good Manufacture Practice Iodine Isotope Benzylguanidine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. [1]
    Lebeda O., Fišer M., Orlova A., Tolmachev V., Sjöström A., and Lundquist H.: in Proc. 14th Radiochemical Conference 14–19 April, Mariánské Lázně, Czech Republic.Google Scholar
  2. [2]
    Fišer M., Kopička K., Hradilek P., Hanč P., Lebeda O., Pánek J., and Vognar M.: in Proc. 14th Radiochemical Conference, 14–19 April, Mariánské Lázně, Czech Republic.Google Scholar

Copyright information

© Institute of Physics, Acad. Sci. CR 2003

Authors and Affiliations

  • K. Kopička
    • 1
  • M. Fišer
    • 1
  • P. Hradilek
    • 1
  • P. Hanč
    • 1
  • O. Lebeda
    • 1
  1. 1.Nuclear Physics InstituteAcademy of Sciences of the Czech RepublicŘež near PragueCzech Republic

Personalised recommendations