Skip to main content
Log in

Parental Depression as a Moderator of Secondary Deficits of Depression in Adult Offspring

  • Original Article
  • Published:
Child Psychiatry and Human Development Aims and scope Submit manuscript

Abstract

This study examined whether having a depressed parent intensifies the secondary deficits that often co-occur with offspring’s depression symptoms. The sample was adult offspring of parents who had been diagnosed with depression 23 years earlier (N = 143) and demographically matched nondepressed parents (N = 197). Respondents completed mailed questionnaires. After controlling for demographic factors, offspring who were more depressed experienced more impairment: physical dysfunction, pain, and disability; anxiety, smoking, and drinking-related problems; poorer social resources; negative events and severe stressors; and reliance on emotional discharge coping. Parental status (depressed or not depressed) was not directly related to offspring impairment once offspring depression symptoms were controlled. However, parental status moderated associations between offspring’s depression severity and their impairment: relationships between depression and impairments were generally stronger for offspring of depressed parents than for offspring of nondepressed parents. Depressed individuals who are offspring of depressed parents may be at particular risk for the secondary deficits of depression.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Gotlib IH, Hammen CL (2002) Handbook of depression. Guilford Press, New York

    Google Scholar 

  2. Goodman SH, Gotlib IH (2002) Children of depressed parents: Mechanisms of risk and implications for treatment. American Psychological Association, Washington, DC doi:10.1037/10449-000

  3. Golinkoff M (2007) Managed care best practices: the road from diagnosis to recovery: access to appropriate care. J Manag Care Pharm 13:S23–S27

    PubMed  Google Scholar 

  4. Aikens JE, Kroenke K, Nease DE Jr, Klinkman MS, Sen A (2008) Trajectories of improvement for six depression-related outcomes. Gen Hosp Psychiatry 30:26–31. doi:10.1016/j.genhosppsych.2007.10.003

    Article  PubMed  Google Scholar 

  5. Alschuler KN, Theisen-Goodvich ME, Haig AJ, Geisser ME (2008) A comparison of the relationship between depression, perceived disability, and physical performance in persons with chronic pain. Eur J Pain 12:757–764. doi:10.1016/j.ejpain.2007.11.003

    Article  PubMed  Google Scholar 

  6. Arnow BA, Hunkeler EM, Blasey CM, Lee J, Constantino MJ, Fireman B, Kraemer HC, Dea R, Robinson R, Hayward C (2006) Comorbid depression, chronic pain, and disability in primary care. Psychosom Med 68:262–268. doi:10.1097/01.psy.0000204851.15499.fc

    Article  PubMed  Google Scholar 

  7. Simms LJ, Gros DF, Watson D, O’Hara MW (2008) Parsing the general and specific components of depression and anxiety with bifactor modeling. Depress Anxiety 25:E34–E46. doi:10.1002/da.20432

    Article  PubMed  Google Scholar 

  8. Friedman-Wheeler DG, Ahrens AH, Haaga DA, McIntosh E, Thorndike FP (2007) Depressive symptoms, depression proneness, and outcome expectancies for cigarette smoking. Cognit Ther Res 31:547–557. doi:10.1007/s10608-006-9064-3

    Article  PubMed  Google Scholar 

  9. Grant BF, Harford TC (1995) Comorbidity between DSM-IV alcohol use disorders and major depression: results of a national survey. Drug Alcohol Depend 39:197–206. doi:10.1016/0376-8716(95)01160-4

    Article  PubMed  Google Scholar 

  10. Graham K, Massak A, Demers A, Rehm J (2007) Does the association between alcohol consumption and depression depend on how they are measured? Alcohol Clin Exp Res 31:78–88. doi:10.1111/j.1530-0277.2006.00274.x

    Article  PubMed  Google Scholar 

  11. Jacobson NS, Martell CR, Dimidjian S (2001) Behavioral activation treatment for depression: returning to contextual roots. Clin Psychol Sci Pract 8:255. doi:10.1093/clipsy/8.3.255

    Article  Google Scholar 

  12. Kendler KS, Karkowski LM, Prescott CA (1999) Causal relationship between stressful life events and the onset of major depression. Am J Psychiatry 837–841

  13. Patton GC, Coffey C, Posterino M, Carlin JB, Bowes G (2003) Life events and early onset depression: cause or consequence? Psychol Med 33:1203–1210. doi:10.1017/S0033291703008626

    Article  PubMed  Google Scholar 

  14. Matheson K, Anisman H (2003) Systems of coping associated with dysphoria, anxiety and depressive illness: a multivariate profile perspective. Stress 6:223–234. doi:10.1080/10253890310001594487

    Article  PubMed  Google Scholar 

  15. Ravindran AV, Matheson K, Griffiths J, Merali Z, Anisman H (2002) Stress, coping, uplifts, and quality of life in subtypes of depression: a conceptual frame and emerging data. J Affect Disord 71:121–130. doi:10.1016/S0165-0327(01)00389-5

    Article  PubMed  Google Scholar 

  16. Cronkite RC, Moos RH, Twohey J, Cohen C, Swindle R Jr (1998) Life circumstances and personal resources as predictors of the ten-year course of depression. Am J Community Psychol 26:255–280. doi:10.1023/A:1022180603266

    Article  PubMed  Google Scholar 

  17. Moos RH, Cronkite RC, Moos BS (1998) Family and extrafamily resources and the 10-year course of treated depression. J Abnorm Psychol 107:450–460. doi:10.1037/0021-843X.107.3.450

    Article  PubMed  Google Scholar 

  18. Weissman MM, Wickramaratne P, Nomura Y, Warner V, Pilowsky D, Verdeli H (2006) Offspring of depressed parents: 20 years later. Am J Psychiatry 163:1001–1008. doi:10.1176/appi.ajp.163.6.1001

    Article  PubMed  Google Scholar 

  19. Ensminger ME, Hanson SG, Riley AW, Juon HS (2003) Maternal psychological distress: adult sons’ and daughters’ mental health and educational attainment. J Am Acad Child Adolesc Psychiatry 42:1108–1115. doi:10.1097/01.chi.0000070261.24125.f8

    Article  PubMed  Google Scholar 

  20. Lieb R, Isensee B, Hofler M, Pfister H, Wittchen HU (2002) Parental major depression and the risk of depression and other mental disorders in offspring: a prospective-longitudinal community study. Arch Gen Psychiatry 59:365–374. doi:10.1001/archpsyc.59.4.365

    Article  PubMed  Google Scholar 

  21. Peisah C, Brodaty H, Luscombe G, Anstey KJ (2004) Children of a cohort of depressed patients 25 years later: psychopathology and relationships. J Affect Disord 82:385–394. doi:10.1016/j.jad.2004.03.002

    PubMed  Google Scholar 

  22. Weissman MM, Warner V, Wickramaratne P, Moreau D, Olfson M (1997) Offspring of depressed parents. 10 years later. Arch Gen Psychiatry 54:932–940. doi:10.1176/appi.ajp.163.6.1001

    PubMed  Google Scholar 

  23. Timko C, Cronkite RC, Berg EA, Moos RH (2002) Children of parents with unipolar depression: a comparison of stably remitted, partially remitted, and nonremitted parents and nondepressed controls. Child Psychiatry Hum Dev 32:165–185. doi:10.1023/A:1017924421229

    Article  PubMed  Google Scholar 

  24. Timko C, Cronkite RC, Swindle R, Robinson RL, Turrubiartes P, Moos RH (2008) Functioning status of adult children of depressed parents: a 23-year follow-up. Psychol Med 38:343–352. doi:10.1017/s0033291707002073

    Article  PubMed  Google Scholar 

  25. Spitzer RL, Endicott J, Robins E (1978) Research diagnostic criteria: rationale and reliability. Arch Gen Psychiatry 35:773–782

    PubMed  Google Scholar 

  26. Billings AG, Moos RH (1984) Treatment experiences of adults with unipolar depression: the influence of patient and life context factors. J Consult Clin Psychol 52:119–131. doi:10.1037/0022-006X.52.1.119

    Article  PubMed  Google Scholar 

  27. Moos RH, Cronkite RC, Finney JW (1992) Health and daily living form manual. Mind Garden, Palo Alto, CA

    Google Scholar 

  28. Moos RH (1993) Coping responses inventory: adult form manual. Psychological Assessment Resources, Inc., Odessa, FL

    Google Scholar 

  29. Moos RH (2004) Coping responses inventory: an update on research applications and validity. Psychological Assessment Resources, Inc., Odessa, FL (manual supplement)

    Google Scholar 

  30. Beck A, Steer R (1987) Manual for the Beck Depression Inventory. Psychological Corporation, San Antonio, TX

    Google Scholar 

  31. Holmes TH, Rahe RH (1967) The social readjustment rating scale. J Psychosom Res 11:213–218. doi:10.1016/0022-3999(67)90010-4

    Article  PubMed  Google Scholar 

  32. Adrian C, Hammen C (1993) Stress exposure and stress generation in children of depressed mothers. J Consult Clin Psychol 61:354–359. doi:10.1037/0022-006X.61.2.354

    Article  PubMed  Google Scholar 

  33. Garber J, Martin NC (2002) Negative cognitions in offspring of depressed parents: Mechanisms of risk and implications for treatment. In: Goodman SH, Gotlib IH (eds) Children of depressed parents: mechanisms of risk and implications for treatment. American Psychological Association, Washington, DC, pp. 121–153. doi:10.1037/10449-005

  34. Latendresse SJ, Rose RJ, Viken RJ, Pulkkinen L, Kaprio J, Dick DM (2008) Parenting mechanisms in links between parents’ and adolescents’ alcohol use behaviors. Alcohol Clin Exp Res 32:322–330. doi:10.1111/j.1530-0277.2007.00583.x

    Article  PubMed  Google Scholar 

  35. Connor-Smith JK, Compas BE, Wadsworth ME, Thomsen AH, Saltzman H (2000) Responses to stress in adolescence: measurement of coping and involuntary stress responses. J Consult Clin Psychol 68:976–992. doi:10.1037/0022-006X.68.6.976

    Article  PubMed  Google Scholar 

  36. Swindle RW Jr, Cronkite RC, Moos RH (1989) Life stressors, social resources, coping, and the 4-year course of unipolar depression. J Abnorm Psychol 98:468–477. doi:10.1037/0022-006X.52.1.119

    Article  PubMed  Google Scholar 

  37. Radke-Yarrow M, Klimes-Dougan B (2002) Parental depression and offspring disorders: A developmental perspective. In: Goodman SH, Gotlib IH (eds) Children of depressed parents: mechanisms of risk and implications for treatment. American Psychological Association, Washington, DC, pp. 155–173. doi:10.1037/10449-006

Download references

Acknowledgments

This work was supported by Eli Lilly and Company and the Department of Veterans Affairs Office of Research and Development (Health Services Research and Development Service). We thank Akash Desai for help with manuscript preparation. The views expressed here are the authors’ and do not necessarily represent the views of the Department of Veterans Affairs.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Christine Timko.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Timko, C., Cronkite, R.C., Swindle, R. et al. Parental Depression as a Moderator of Secondary Deficits of Depression in Adult Offspring. Child Psychiatry Hum Dev 40, 575–588 (2009). https://doi.org/10.1007/s10578-009-0145-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10578-009-0145-x

Keywords

Navigation