Child Psychiatry and Human Development

, Volume 38, Issue 1, pp 47–55 | Cite as

Child Behavior Checklist Profiles of Children and Adolescents with and at High Risk for Developing Bipolar Disorder

  • Lisa L. Giles
  • Melissa P. DelBello
  • Kevin E. Stanford
  • Stephen M. Strakowski
Original Paper


In order to recognize behavioral patterns in children and adolescents at risk for developing bipolar disorder, this study examined Child Behavior Checklist (CBCL) profiles of bipolar offspring both with (BD group) and without (“at-risk” or AR group) bipolar disorder themselves. The BD youth had three CBCL subscale T scores ≥70 (attention problems, delinquent behavior, and aggression) and scored significantly higher than healthy comparison youth on all CBCL subscales. AR youth did not have any T scores ≥70; however, they scored higher than healthy comparisons in the anxiety/depression, attention problems, aggression, and withdrawal subscales. AR and BD youth differed significantly on all scales except somatic complaints and anxiety/depression.


Bipolar disorder Children of bipolar parents Child behavior checklist Prodromal symptoms Risk factors Behavioral problems 


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This study was supported by the Stanley Medical Research Institute and NIMH Grant #MH 063373. This work was presented in part at the American Academy of Child and Adolescent Psychiatry Meeting in Toronto, Ontario, October 2005.


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Copyright information

© Springer Science+Business Media, LLC 2006

Authors and Affiliations

  • Lisa L. Giles
    • 1
    • 2
  • Melissa P. DelBello
    • 1
    • 3
  • Kevin E. Stanford
    • 1
  • Stephen M. Strakowski
    • 1
  1. 1.Division of Bipolar Disorders ResearchUniversity of Cincinnati College of MedicineCincinnatiUSA
  2. 2.Division of Child and Adolescent PsychiatryCincinnati Children’s Hospital Medical CenterCincinnatiUSA
  3. 3.Department of PsychiatryUniversity of Cincinnati College of MedicineCincinnatiUSA

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