21st International Colloquium on Animal Cytogenetics and Gene Mapping
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Edited by:L. Iannuzzi, A. Perucatti, A. Iannuzzi, A. Pauciullo, V. Genualdo, D. Incarnato, L. Keller(CNR-ISPAAM, Naples, Italy)
Molecular cytogenetics in veterinary diagnosis and research
Malcolm A. Ferguson-Smith (email@example.com)
Department of Veterinary Medicine, Cambridge University, Madingley Road, Cambridge CB3 0ES, UK
Fifty years ago Ingemar Gustavsson made the first observation of a chromosome abnormality in a farm animal. The common rob1/29 translocation in cattle has been associated with reduced fertility, prompting efforts at eradication. Since then many other chromosome abnormalities have been identified in domestic species, including sex chromosome abnormalities in race horses, and these have been discussed at many meetings of the ICACGM. Interest in diagnostic veterinary cytogenetics has grown alongside research into comparative genomics and karyotype evolution of farm animals. The current place of molecular cytogenetics in both diagnosis and...