Cellulose

, Volume 25, Issue 1, pp 319–329 | Cite as

Entrapment of peppermint oil using cellulose nanocrystals

Original Paper
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Abstract

Cellulose nanoparticles possess distinct advantages in delivery of different components because of their non-cytotoxicity and numerous surface hydroxyl groups. In this study, cellulose nanocrystals (CNC) were extracted from pistachio shell (PS). Alkali and bleaching treatments were performed to remove hemicellulose and lignin and purification of cellulose. Acid hydrolysis was performed in order to eliminate amorphous parts of cellulose and produce CNC. According to FE-SEM images, the diameter of CNCs was 36.6 ± 8.9 nm. Encapsulation of peppermint oil (PO) as a common aroma at different concentrations (10–50% V:W) was accomplished using CNC. CNC–PO with 50% encapsulant had the highest encapsulation efficiency and loading capacity. Release studies for all the samples were carried out in simulated saliva for 160 min and release kinetic behavior was evaluated by various mathematical models. FTIR analysis approved entrapment of PO using CNC by hydrogen bonding. XRD analysis showed that no remarkable changes in crystallinity of the CNC were occurred due to encapsulation. The results of this study indicated the possibility of production of CNC from PS and their application as the environmental friendly materials for delivery of aroma.

Keywords

Cellulose nanocrystals Peppermint oil Encapsulation Release behavior 

References

  1. Adamiec J, Kalemba D (2006) Microencapsulation of peppermint oil during spray drying. In: Proceedings of the XIVth international workshop on bioencapsulation, pp 289–292Google Scholar
  2. Alankar S (2009) A review on peppermint oil. Asian J Pharm Clin Res 2:27–33Google Scholar
  3. Al-Bayati FA (2009) Isolation and identification of antimicrobial compound from Mentha longifolia L. leaves grown wild in Iraq. Ann Clin Microbiol Antimicrob 8:20CrossRefGoogle Scholar
  4. Almedeij J (2012) Modeling pan evaporation for Kuwait by multiple linear regression. Sci World J 2012:1–9. http://doi.org/10.1100/2012/574742 Google Scholar
  5. Amin MCIM, Ahmad N, Halib N, Ahmad I (2012) Synthesis and characterization of thermo-and pH-responsive bacterial cellulose/acrylic acid hydrogels for drug delivery. Carbohyd Polym 88:465–473CrossRefGoogle Scholar
  6. Apaydin-Varol E, Pütün E, Pütün AE (2007) Slow pyrolysis of pistachio shell. Fuel 86:1892–1899.  https://doi.org/10.1016/j.fuel.2006.11.041 CrossRefGoogle Scholar
  7. Bakry AM, Fang Z, Ni Y, Cheng H, Chen YQ, Liang L (2016) Stability of tuna oil and tuna oil/peppermint oil blend microencapsulated using whey protein isolate in combination with carboxymethyl cellulose or pullulan. Food Hydrocoll 60:559–571CrossRefGoogle Scholar
  8. Baranauskienė R, Bylaitė E, Žukauskaitė J, Venskutonis RP (2007) Flavor retention of peppermint (Mentha piperita L.) essential oil spray-dried in modified starches during encapsulation and storage. J Agric Food Chem 55:3027–3036CrossRefGoogle Scholar
  9. Davis RE, Hartman CW, Fincher JH (1971) Dialysis of ephedrine and pentobarbital from whole human saliva and simulated saliva. J Pharm Sci 60:429–432CrossRefGoogle Scholar
  10. Fu Y, Kao WJ (2010) Drug release kinetics and transport mechanisms of non-degradable and degradable polymeric delivery systems. Expert Opin Drug Deliv 7:429–444CrossRefGoogle Scholar
  11. Ghayempour S, Montazer M, Rad MM (2015) Tragacanth gum as a natural polymeric wall for producing antimicrobial nanocapsules loaded with plant extract. Int J Biol Macromol 81:514–520CrossRefGoogle Scholar
  12. Henrique MA, Silverio HA, Flauzino Neto WP, Pasquini D (2013) Valorization of an agro-industrial waste, mango seed, by the extraction and characterization of its cellulose nanocrystals. J Environ Manag 121:202–209.  https://doi.org/10.1016/j.jenvman.2013.02.054 CrossRefGoogle Scholar
  13. Higuchi T (1963) Mechanism of sustained-action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J Pharm Sci 52:1145–1149CrossRefGoogle Scholar
  14. Huq T et al (2012) Nanocrystalline cellulose (NCC) reinforced alginate based biodegradable nanocomposite film. Carbohyd Polym 90:1757–1763CrossRefGoogle Scholar
  15. Huq T, Riedl B, Bouchard J, Salmieri S, Lacroix M (2014) Microencapsulation of nisin in alginate-cellulose nanocrystal (CNC) microbeads for prolonged efficacy against Listeria monocytogenes. Cellulose 21:4309–4321CrossRefGoogle Scholar
  16. Jackson JK, Letchford K, Wasserman BZ, Ye L, Hamad WY, Burt HM (2011) The use of nanocrystalline cellulose for the binding and controlled release of drugs. Int J Nanomed 6:321Google Scholar
  17. Khan RA, Salmieri S, Dussault D, Uribe-Calderon J, Kamal MR, Safrany A, Lacroix M (2010) Production and properties of nanocellulose-reinforced methylcellulose-based biodegradable films. J Agric Food Chem 58:7878–7885CrossRefGoogle Scholar
  18. Koo SY, Cha KH, Song DG, Chung D, Pan CH (2014) Microencapsulation of peppermint oil in an alginate–pectin matrix using a coaxial electrospray system. Int J Food Sci Technol 49:733–739CrossRefGoogle Scholar
  19. Kopcha M, Tojo KJ, Lordi NG (1990) Evaluation of methodology for assessing release characteristics of thermosoftening vehicles. J Pharm Pharmacol 42:745–751CrossRefGoogle Scholar
  20. Lin N, Huang J, Chang PR, Feng L, Yu J (2011) Effect of polysaccharide nanocrystals on structure, properties, and drug release kinetics of alginate-based microspheres. Colloids Surf B 85:270–279CrossRefGoogle Scholar
  21. Madene A, Jacquot M, Scher J, Desobry S (2006) Flavour encapsulation and controlled release–a review. Int J Food Sci Technol 41:1–21CrossRefGoogle Scholar
  22. Moritz S et al (2014) Active wound dressings based on bacterial nanocellulose as drug delivery system for octenidine. Int J Pharm 471:45–55CrossRefGoogle Scholar
  23. Müller A, Ni Z, Hessler N, Wesarg F, Müller FA, Kralisch D, Fischer D (2013) The biopolymer bacterial nanocellulose as drug delivery system: investigation of drug loading and release using the model protein albumin. J Pharm Sci 102:579–592CrossRefGoogle Scholar
  24. Peng BL, Dhar N, Liu H, Tam K (2011) Chemistry and applications of nanocrystalline cellulose and its derivatives: a nanotechnology perspective. Can J Chem Eng 89:1191–1206CrossRefGoogle Scholar
  25. Peppas NA, Sahlin JJ (1989) A simple equation for the description of solute release. III. Coupling of diffusion and relaxation. Int J Pharm 57:169–172CrossRefGoogle Scholar
  26. Ritger PL, Peppas NA (1987) A simple equation for description of solute release II. Fickian and anomalous release from swellable devices. J Controll Release 5:37–42CrossRefGoogle Scholar
  27. Rowell RM (2012) Handbook of wood chemistry and wood composites. CRC Press, Boca RatonCrossRefGoogle Scholar
  28. Segal L, Creely JJ, Martin AE, Conrad CM (1959) An empirical method for estimating the degree of crystallinity of native cellulose using the X-Ray diffractometer textile. Res J 29:786–794Google Scholar
  29. Shang W, Huang J, Luo H, Chang PR, Feng J, Xie G (2013) Hydrophobic modification of cellulose nanocrystal via covalently grafting of castor oil. Cellulose 20:179–190CrossRefGoogle Scholar
  30. Taheri A, Mohammadi M (2015) The use of cellulose nanocrystals for potential application in topical delivery of hydroquinone. Chem Biol Drug Des 86:102–106CrossRefGoogle Scholar
  31. Taneja SC, Chandra S (2012) 20-Mint. In: Peter KV (ed) Handbook of herbs and spices, 2nd edn. Woodhead Publishing, Boca Raton, pp 366–387CrossRefGoogle Scholar
  32. Ye C, Malak ST, Hu K, Wu W, Tsukruk VV (2015) Cellulose nanocrystal microcapsules as tunable cages for nano-and microparticles. ACS Nano 9:10887–10895CrossRefGoogle Scholar
  33. Yu H, Qin Z, Liang B, Liu N, Zhou Z, Chen L (2013) Facile extraction of thermally stable cellulose nanocrystals with a high yield of 93% through hydrochloric acid hydrolysis under hydrothermal conditions. J Mater Chem A 1:3938–3944CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media B.V., part of Springer Nature 2017

Authors and Affiliations

  1. 1.Departments of Food Science and Technology, College of AgricultureIsfahan University of TechnologyIsfahanIran

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