, Volume 25, Issue 1, pp 829–841 | Cite as

In situ synthesis of Cu/Cu2O nanoparticles on the TEMPO oxidized cotton fabrics

  • Darka Marković
  • Matea Korica
  • Mirjana Kostić
  • Željko Radovanović
  • Zoran Šaponjić
  • Miodrag Mitrić
  • Maja Radetić
Original Paper


In situ synthesis of Cu/Cu2O nanoparticles on the cotton fabric discussed in this study relies on adsorption of Cu2+-ions by carboxylate groups generated through the TEMPO-mediated oxidation of cellulose and their subsequent reduction by sodium borohydride. In order to establish the influence of aldehyde and carboxylate groups on the nanoparticles formation, the duration of TEMPO-mediated oxidation was varied. Chemical changes induced by TEMPO-mediated oxidation were evaluated by titrimetric determination of the amounts of aldehyde and carboxylic groups in cotton and FTIR spectroscopy. The presence of Cu/Cu2O nanoparticles on the cotton fabric was confirmed by FE-SEM, AAS and XRD analyses. Antimicrobial activity of synthesized nanoparticles was tested against Gram-negative bacteria E. coli, Gram-positive bacteria S. aureus and fungi C. albicans. The extension of TEMPO oxidation time led to an increase of carboxylate group content and consequently, formation of larger amounts of Cu/Cu2O nanoparticles. All fabricated textile nanocomposites provided excellent antibacterial and acceptable antifungal activity. They also ensured a controlled release of Cu2+-ions in physiological solution which is an imperative for infection prevention.


Cotton fabric Cu/Cu2O nanoparticles TEMPO oxidation Antimicrobial activity Cu2+-ions release 



The financial support for this study was provided by the Ministry of Education, Science and Technological Development of Republic of Serbia (Projects Nos. 172056 and 172029). We gratefully acknowledge dr M. Radoičić (University of Belgrade, Serbia) for providing FTIR measurements.

Supplementary material

10570_2017_1566_MOESM1_ESM.docx (26 kb)
Supplementary material 1 (DOCX 26 kb)


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Copyright information

© Springer Science+Business Media B.V., part of Springer Nature 2017

Authors and Affiliations

  • Darka Marković
    • 2
  • Matea Korica
    • 2
  • Mirjana Kostić
    • 1
  • Željko Radovanović
    • 2
  • Zoran Šaponjić
    • 3
  • Miodrag Mitrić
    • 3
  • Maja Radetić
    • 1
  1. 1.Faculty of Technology and MetallurgyUniversity of BelgradeBelgradeSerbia
  2. 2.Innovation Center of the Faculty of Technology and MetallurgyUniversity of BelgradeBelgradeSerbia
  3. 3.Vinča Institute of Nuclear SciencesUniversity of BelgradeBelgradeSerbia

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