Antibacterial modification of cellulose fibers by grafting β-cyclodextrin and inclusion with ciprofloxacin
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Antibacterial-modified cellulose fiber was prepared by covalently bonding β-cyclodextrin (β-CD) with cellulose fiber via citric acid (CA) as crosslinking agent, followed by the inclusion of ciprofloxacin hydrochloride (CipHCl) as antibiotic. Effects of reaction time, temperature, concentration of β-cyclodextrin citrate (CA-β-CD) and pH on the grafting reaction were investigated, and the grafting ratio of β-CD onto cellulose fibers was 9.7 % at optimal conditions; the loading and releasing behaviors of CipHCl into/from β-CD grafted cellulose fibers were also revealed, the load amount of CipHCl into grafted cellulose fibers increased remarkably, and the release of CipHCl from the grafted cellulose fibers was prolonged. The microstructure, phase and thermal stability of modified cellulose fibers were characterized by FT-IR, 13C CPMAS NMR, X-ray diffraction and TGA. Considerably longer bacterial activity against E. coli and S. aureus was observed for grafted fibers loading CipHCl compared to virgin ones. Optical and mechanical properties of the paper sheets decreased generally with more antibacterial-modified fibers added.
KeywordsCellulose fiber β-Cyclodextrin Grafting Antibacterial activity
This work was supported by the grants from the National Natural Science Foundation of China (grant nos. 31200457 and 31270636), NSERC Sentinel Bioactive Paper Network (Canada) and the Fundamental Research Funds for the Central Universities (2013ZZ0072).
- Denter U, Schollmeyer E (1997) Surface modification of synthetic and natural fibres by fixation of cyclodextrin derivatives. In: Proceedings of the 8th international symposium on cyclodextrins, pp 559–564Google Scholar
- Dipa R, Mahuya D, Debarati M (2009) Influence of alkali treatment on creep properties and crystallinity of jute fibres. Bioresources 4(2):730–739Google Scholar
- Leitner J, Zuckerstätter G, Schmied F, Kandelbauer A (2013) Modifications in the bulk and the surface of unbleached lignocellulosic fibers induced by heat treatment without water removal: effects on tensile properties of unrefined kraft pulp. Euro J Wood Wood Prod 71(1):101–110CrossRefGoogle Scholar
- Lu D, Zhou X, Xing X, Wang X, Liu Z (2004) Quaternary ammonium salt (QAS) grafted cellulose fiber-preparation and anti-bacterial function. Acta Polym Sin 1:107–113Google Scholar