Catalysis Letters

, Volume 148, Issue 6, pp 1651–1658 | Cite as

New Crown Ether-Based Nano Ionic Liquid ([DB-18-C-6K+][OH] nIL): A Versatile Nanocatalyst for the Synthesis of Spiro[indoline-3,2′-quinoline] Derivatives via the Cascade Four-Component Reaction of Arylamines, Dialkylacetylenedicarboxylates, Isatins and Dimedone

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Abstract

A new nano-size crown ether-based ionic liquid on the basis of dibenzo-18-crown-6 ([DB-18-C-6K+][OH] nIL) has been synthesized via a simple procedure and characterized through fourier transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, high-resolution scanning electron microscopy, energy-dispersive X-ray spectroscopy, thermogravimetric/differential thermal analysis, and UV–Vis spectroscopy techniques The obtained catalyst has been utilized for the one-pot, four-component synthesis of spiro[indoline-3,2′-quinoline] derivatives from the combination of isatins, amines, dimedone, and dialkylacetylenedicarboxylates. The advantages of this protocol included the use of common and easily-available starting materials, utilizing ambient temperature, non-toxic and inexpensive reagent usage, high yields of products, and operationally simple procedure.

Graphical Abstract

Keywords

Crown ether-based nano ionic liquid Spiro[indoline-3,2′-quinoline] Spiro compounds Multi-component reaction Isatin Dialkylacetylenedicarboxylates 

Notes

Acknowledgements

The researchers appreciate Alzahra University research council for partial financial support of this work.

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Chemistry Department, School of Physics and ChemistryAlzahra UniversityTehranIran

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