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New Crown Ether-Based Nano Ionic Liquid ([DB-18-C-6K+][OH−] nIL): A Versatile Nanocatalyst for the Synthesis of Spiro[indoline-3,2′-quinoline] Derivatives via the Cascade Four-Component Reaction of Arylamines, Dialkylacetylenedicarboxylates, Isatins and Dimedone

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Abstract

A new nano-size crown ether-based ionic liquid on the basis of dibenzo-18-crown-6 ([DB-18-C-6K+][OH−] nIL) has been synthesized via a simple procedure and characterized through fourier transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, high-resolution scanning electron microscopy, energy-dispersive X-ray spectroscopy, thermogravimetric/differential thermal analysis, and UV–Vis spectroscopy techniques The obtained catalyst has been utilized for the one-pot, four-component synthesis of spiro[indoline-3,2′-quinoline] derivatives from the combination of isatins, amines, dimedone, and dialkylacetylenedicarboxylates. The advantages of this protocol included the use of common and easily-available starting materials, utilizing ambient temperature, non-toxic and inexpensive reagent usage, high yields of products, and operationally simple procedure.

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Acknowledgements

The researchers appreciate Alzahra University research council for partial financial support of this work.

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Authors and Affiliations

  1. Chemistry Department, School of Physics and Chemistry, Alzahra University, Vanak, Tehran, Iran

    Kobra Nikoofar & Shiva Khani

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  1. Kobra Nikoofar
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  2. Shiva Khani
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Correspondence to Kobra Nikoofar.

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Nikoofar, K., Khani, S. New Crown Ether-Based Nano Ionic Liquid ([DB-18-C-6K+][OH−] nIL): A Versatile Nanocatalyst for the Synthesis of Spiro[indoline-3,2′-quinoline] Derivatives via the Cascade Four-Component Reaction of Arylamines, Dialkylacetylenedicarboxylates, Isatins and Dimedone. Catal Lett 148, 1651–1658 (2018). https://doi.org/10.1007/s10562-018-2391-7

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