New Crown Ether-Based Nano Ionic Liquid ([DB-18-C-6K+][OH−] nIL): A Versatile Nanocatalyst for the Synthesis of Spiro[indoline-3,2′-quinoline] Derivatives via the Cascade Four-Component Reaction of Arylamines, Dialkylacetylenedicarboxylates, Isatins and Dimedone
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A new nano-size crown ether-based ionic liquid on the basis of dibenzo-18-crown-6 ([DB-18-C-6K+][OH−] nIL) has been synthesized via a simple procedure and characterized through fourier transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, high-resolution scanning electron microscopy, energy-dispersive X-ray spectroscopy, thermogravimetric/differential thermal analysis, and UV–Vis spectroscopy techniques The obtained catalyst has been utilized for the one-pot, four-component synthesis of spiro[indoline-3,2′-quinoline] derivatives from the combination of isatins, amines, dimedone, and dialkylacetylenedicarboxylates. The advantages of this protocol included the use of common and easily-available starting materials, utilizing ambient temperature, non-toxic and inexpensive reagent usage, high yields of products, and operationally simple procedure.
KeywordsCrown ether-based nano ionic liquid Spiro[indoline-3,2′-quinoline] Spiro compounds Multi-component reaction Isatin Dialkylacetylenedicarboxylates
The researchers appreciate Alzahra University research council for partial financial support of this work.
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Conflict of interest
The authors declare that they have no conflict of interest.
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