New Crown Ether-Based Nano Ionic Liquid ([DB-18-C-6K+][OH−] nIL): A Versatile Nanocatalyst for the Synthesis of Spiro[indoline-3,2′-quinoline] Derivatives via the Cascade Four-Component Reaction of Arylamines, Dialkylacetylenedicarboxylates, Isatins and Dimedone
A new nano-size crown ether-based ionic liquid on the basis of dibenzo-18-crown-6 ([DB-18-C-6K+][OH−] nIL) has been synthesized via a simple procedure and characterized through fourier transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, high-resolution scanning electron microscopy, energy-dispersive X-ray spectroscopy, thermogravimetric/differential thermal analysis, and UV–Vis spectroscopy techniques The obtained catalyst has been utilized for the one-pot, four-component synthesis of spiro[indoline-3,2′-quinoline] derivatives from the combination of isatins, amines, dimedone, and dialkylacetylenedicarboxylates. The advantages of this protocol included the use of common and easily-available starting materials, utilizing ambient temperature, non-toxic and inexpensive reagent usage, high yields of products, and operationally simple procedure.
KeywordsCrown ether-based nano ionic liquid Spiro[indoline-3,2′-quinoline] Spiro compounds Multi-component reaction Isatin Dialkylacetylenedicarboxylates
The researchers appreciate Alzahra University research council for partial financial support of this work.
Compliance with Ethical Standards
Conflict of interest
The authors declare that they have no conflict of interest.
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