Catalysis Letters

, Volume 105, Issue 3–4, pp 229–232 | Cite as

A Simple Environmentally-friendly Method for the Selective Synthesis of 1,5-benzodiazepine Derivatives using Zeolite Catalyst

  • Adrienn Hegedüs
  • Zoltán Hell
  • Attila Potor

The modified small pore size zeolite E4a has been found to be an efficient catalyst for the regioselective synthesis of 2,3-dihydro-1H-1,5-benzodiazepines from o-phenylenediamine and ketones. This method is simple, cheap, environmentally-friendly and give the benzodiazepines in high yield.

Key words

1,5-benzodiazepines heterocycles zeolites green chemistry 


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Copyright information

© Springer Science+Business Media, Inc. 2005

Authors and Affiliations

  1. 1.Department of Organic Chemical TechnologyBudapest University of Technology and EconomicsBudapestHungary

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