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Catalysis Letters

, Volume 104, Issue 3–4, pp 151–156 | Cite as

Enantioselective Hydrolytic Kinetic Resolution of 1,2-epoxy-3-phenoxy Propane Derivatives by New Chiral (Salen) Cobalt Complexes

  • Santosh Singh Thakur
  • Wenji Li
  • Chang-Kyo Shin
  • Geon-Joong Kim
Article

The enantioselective hydrolytic kinetic resolution (HKR) of racemic terminal epoxides catalyzed by new chiral (Salen) Co complex linked with Al or Ga provides a practical access of the enantiomerically enriched terminal epoxides (>98% ee) and 1,2-diols simultaneously. In the present method, bimetallic catalysts show dramatically increased reaction rates with high enantioselectivity relative to the monomeric salen catalyst.

Key words

hydrolytic kinetic resolution chiral cobalt salen catalyst terminal epoxides 

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Copyright information

© Springer Science+Business Media, Inc. 2005

Authors and Affiliations

  • Santosh Singh Thakur
    • 1
  • Wenji Li
    • 1
  • Chang-Kyo Shin
    • 1
  • Geon-Joong Kim
    • 1
  1. 1.Department of Chemical EngineeringInha UniversityIncheonSouth Korea

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