Abstract
Psoriasis is a chronic inflammatory autoimmune disease with undefined etiology. It affects 2–3% of the worldwide population. The unsatisfactory outcome of variable treatments of the disease is partially due to the poor compliance of the present therapies with more or less side effects. As known, the human amniotic membrane is a popular intervention for many diseases. Amniotic membrane has been found recently to possess antimicrobial, anti-inflammatory and immunosuppressive properties. The irradiated amniotic membrane was used in this study as a topical application for 4 weeks on localized lesions in cases of mild psoriasis. The results presented herein provide a solid basis for the amniotic membrane to be used as a promising intervention for psoriasis treatment in the future.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Abomaray FM, Al Jumah MA, Kaionis B et al (2015) Human chorionic villus mesenchymal stem cells modify the function of human dendritic cells, and induce an anti-inflammatory phenotype in CD1 + dendritic cells. Stem Cell Rev 11:423–441
Alikarami F, Yari F, Amirizdeh N et al (2015) The immunosuppressive activity of amniotic membrane mesenchymal stem cells on T lymphocytes. Avicenna J Med Biotechnol 7(3):90–96
Bata-Csorgo Z, Hammerberg C, Voorhees JJ, Cooper KD (1995) Intralesional T-lymphocyte activation as a mediator of psoriatic epidermal hyperplasia. J Invest Dermatol 105(1 suppl):89s–94s
Chen CP, Chen YY, Huang JP, Wu YH (2014) The effect of conditioned medium derived from human placental multipotent mesenchymal stromal cells on neutrophils; Possible implications for placental infection. Hum Reprod 20:1117–1125
Donders R, Vanheusden M, Bogie JF et al (2015) Human Wharton’s jelly-derived stem cells display immunomodulatory properties and transiently improve rate experimental autoimmune encephalomyelitis. Cell Transpl 24:2077–2098
Faulk WP, Matthews R, Stevens PJ, Bennett JP, Burgos H, Hsi BL (1980) Human amnion as an adjunct in wound healing. Lancet 1:1156–1158
Gisondi P, Di Mercurio M, Idolazzi L, Girolomoni G (2015) Concept of remission in chronic plaque psoriasis. J Rheumatol Suppl 93:57–60
Hao Y, Ma DH, Hwang DG, Kim WS, Zhang F (2000) Identification of antiangiogenic and anti-inflammatory proteins in human amniotic membrane. Cornea 19:348–352
John T, Foulks GN, John ME, Cheng K, Hu D (2002) Amniotic membrane in the surgical management of acute toxic epidermal necrolysis. Ophthalmology 109(2):351–360
Kim JC, Tseng SC (1995) The effects on inhibition of corneal neovascularization after human amniotic membrane transplantation in severely damaged rabbit corneas. Korean J Ophthalmol 9:32–46
Kronsteiner B, Wolbank S, Peterbauer A et al (2011) Human mesenchymal stem cells from adipose tissue and amnion influence T-cells depending on stimulation method and presence of other immune cells. Stem cells Dev 20:2115–2126
Li J, Koike-Soko C, Sugimoto J et al (2015) Human amnion-derived stem cells have immunosuppressive properties on NK cells and monocytes. Cell Transpl 24:2065–2076
Ma L, Zhou Z, Zhang D et al (2012) Immunosuppressive function of mesenchymal stem cells from human umbilical cord matrix in immune thrombocytopenia patients. Thromb Haemost 107:937–950
Magatti M, Caruso M, De Munari S et al (2015) Human amniotic membrane-derived mesenchymal and epithelial cells exert different effects on monocyte-derived dendritic cell differentiation and function. Cell Transpl 24:1733–1752
Mahil SK, Capon F, Barker JN (2016) Update on Psoriasis immunopathogenesis and targeted immunotherapy. Semin immunopathol 38:11–27
Marsit N, Dwejen S, Saad I, Abdalla S, Shaab A, Salem S, Khanfas E, Hasan A, Mansur M, Abdul Sammad M (2014) Substantiation of 25 kGy radiation sterilization dose for banked air dried amniotic membrane and evaluation of personnel skill in influencing finished product bioburden. Cell Tissue Bank 15(4):603–611
McDonald CA, Payne NL, Sun G et al (2015) Immunosuppressive potential of human amnion epithelial cells in the treatment of experimental autoimmune encephalomyelitis. J Neuroinflammation 3(12):112
Pianta S, Bonassi Signoroni P, Muradore L et al (2015) Amniotic membrane mesenchymal cells-derived factors skew T cell polarization toward Treg and downregulate Th 1 and Th 17 cells subsets. Stem cell Rev 11(3):394–407
Redondo P, de Azcarate AG, Marqués L et al (2011) Amniotic membrane as a scaffold for melanocyte transplantation in patients with stable vitiligo. Dermatol Res Prac. https://doi.org/10.1155/2011/532139
Russo A, Bonci P, Bonci P (2012) The effects of different preservation processes on the total protein and growth factor content in a new biological product developed from human amniotic membrane. Cell Tissue Bank 13(2):353–361
Troyer DL, Weiss ML (2008) Wharton’s jelly-derived cells are primitive stromal cell population. Stem Cells 26:591–599
Uberti MG, Pierpont YN, Ko F, Wright TE, Smith CA, Cruse CW, Robson MC, Payne WG (2010) Amnion-derived cellular cytokine solution (ACCS) promotes migration of keratinocytes and fibroblasts. Ann Plast Surg 64:632–635
Yamahara K, Harada K, Ohshima M et al (2014) Comparison of angiogenic, cytoprotective, and immunosuppressive properties of human amnion and chorion-derived mesenchymal stem cells. PLoS ONE 9(2):e88319. https://doi.org/10.1371/journal.pone.0088319 (eCollection 2014)
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Radwan, N.K., Ibrahim, N.F. & Bashandy, A.S. Uses of gamma irradiated amniotic membrane as an alternative method in psoriasis treatment. Cell Tissue Bank 19, 733–741 (2018). https://doi.org/10.1007/s10561-018-9727-9
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10561-018-9727-9