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Cell and Tissue Banking

, Volume 14, Issue 1, pp 45–52 | Cite as

An oral cancer biobank initiative: a platform for multidisciplinary research in a developing country

  • Rosnah Binti Zain
  • Vimmitra Athirajan
  • Wan Maria Nabillah Ghani
  • Ishak Abdul Razak
  • Raja Jalaludin Raja Latifah
  • Siti Mazlipah Ismail
  • Atiya Abdul Sallam
  • Anita Zarina Bustam
  • Zainal Ariff Abdul Rahman
  • Adam Hussien
  • Norain Talib
  • Sok Ching Cheong
  • Amin Jallaludin
Article

Abstract

Identification of diagnostic markers for early detection and development of novel and therapeutic agents for effective patient management are the main motivation for cancer research. Biological specimens from large cohort and case-control studies which are crucial in providing successful research outcomes are often the limiting factor that hinders research efforts, especially in developing countries. Therefore, the Malaysian Oral Cancer Database and Tissue Bank System (MOCDTBS) were established to systematically collect large number of samples with comprehensive sociodemographic, clinicopathological, management strategies, quality of life and associated patient follow-up data to facilitate oral cancer research in Malaysia. The MOCDTBS also promotes sharing among researchers and the development of a multidisciplinary research team. The following article aims to describe the process of setting-up and managing the MOCDTBS.

Keywords

Oral cancer Biobank Malaysia Multidisciplinary team 

Notes

Acknowledgments

The development of the biobank was supported by grants from the Ministry of Science, Technology and Innovation (MOSTI) Malaysia: Intensified Research in Priority Areas (IRPA) of the 8th Malaysia Plan (RMK8) Fund [project number: 06-02-03-0174 PR 0054/05-05; 06-00-00-0000] and E-Science Fund [project number: 06-01-03-SF0089]. The continuation and maintenance of the biobank are currently supported by the University of Malaya through an operative and human resource budget to the Oral Cancer Research and Coordinating Centre (OCRCC), Faculty of Dentistry. The authors would like to thank Dr. Wan Mahadzir Wan Mustafa, Dr. Thomas Abraham, Dr. Norma Jalil, Dr. Yuen Kar Mun, Dr. Tay Keng Kiong, all research coordinators and staffs from Oral Health Division, Ministry of Health Malaysia at various participating hospitals for their invaluable effort in data and specimen collection. Our deepest gratitude is also dedicated to all members of this project for their support and endless effort in developing and maintaining the biobank.

Conflicts of interest

None declared.

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Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • Rosnah Binti Zain
    • 1
    • 2
  • Vimmitra Athirajan
    • 1
  • Wan Maria Nabillah Ghani
    • 1
  • Ishak Abdul Razak
    • 1
    • 3
  • Raja Jalaludin Raja Latifah
    • 1
  • Siti Mazlipah Ismail
    • 1
    • 4
  • Atiya Abdul Sallam
    • 1
  • Anita Zarina Bustam
    • 5
  • Zainal Ariff Abdul Rahman
    • 4
  • Adam Hussien
    • 6
  • Norain Talib
    • 7
  • Sok Ching Cheong
    • 4
    • 8
  • Amin Jallaludin
    • 9
  1. 1.Oral Cancer Research and Coordinating Centre, Faculty of DentistryUniversity MalayaLembah Pantai, Kuala LumpurMalaysia
  2. 2.Department of Oral Pathology, Oral Medicine and Periodontology, Faculty of DentistryUniversity MalayaKuala LumpurMalaysia
  3. 3.Department of Community Dentistry, Faculty of DentistryUniversity MalayaKuala LumpurMalaysia
  4. 4.Department of Oral and Maxillofacial Surgery, Faculty of DentistryUniversity MalayaKuala LumpurMalaysia
  5. 5.Dean’s Office, Faculty of MedicineUniversity MalayaKuala LumpurMalaysia
  6. 6.Department of Restorative Dentistry, School of Dental SciencesUniversiti Sains MalaysiaKubang Kerian, KelantanMalaysia
  7. 7.Oral Health DivisionMinistry of HealthPutrajayaMalaysia
  8. 8.Oral Cancer Research TeamCancer Research Initiatives FoundationKuala LumpurMalaysia
  9. 9.Department of Otorhinolaringology, Faculty of MedicineUniversity MalayaKuala LumpurMalaysia

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