Cell and Tissue Banking

, Volume 13, Issue 4, pp 623–629 | Cite as

Neural stem cells in the ischemic and injured brain: endogenous and transplanted

  • Jing DongEmail author
  • Baohua Liu
  • Lei Song
  • Lei Lu
  • Haitao Xu
  • Yue Gu


Neural stem cells functions as the pool of new neurons in adult brain, and plays important roles in normal brain function. Additionally, this pool reacts to brain ischemia, hemorrhage, trauma and many kinds of diseases, serving as endogenous repair mechanisms. The present manuscript discussed the responses of adult neurogenesis to brain ischemia and other insults, then the potential of neural stem cell transplantation therapy to treat such brain injury conditions.


Neurogenesis Ischemia Inflammation Autologous transplantation Neural stem cell 


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Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  • Jing Dong
    • 1
    Email author
  • Baohua Liu
    • 2
  • Lei Song
    • 2
  • Lei Lu
    • 2
  • Haitao Xu
    • 3
  • Yue Gu
    • 4
  1. 1.Neurology Department, General HospitalJiHa Group Company, JilinJilinChina
  2. 2.Neurology Department, First HospitalJilin UniversityChangchunChina
  3. 3.Ophthalmology Department, Second HospitalJilin UniversityChangchunChina
  4. 4.Respiratory Department, First HospitalJilin UniversityChangchunChina

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