Advertisement

Supply of human allograft tissue in Canada

  • Jonathan R. T. Lakey
  • Mohammadreza Mirbolooki
  • Christina Rogers
  • Jim Mohr
Article

Abstract

There is relatively little known about the supply for allograft tissues in Canada. The major aim of this study is to quantify the current or “Known Supply” of human allograft tissue (bone, tendons, soft tissue, cardiovascular, ocular and skin) from known tissue banks in Canada, to estimate the “Unknown Supply” of human allograft tissue available to Canadian users from other sources, and to investigate the nature and source of these tissue products. Two surveys were developed; one for tissue banks processing one or more tissue types and the other specific to eye banks. Thirty nine sites were initially identified as potential tissue bank respondent sites. Of the 39 sites, 29 sites indicated that they were interested in participating or would consider completing the survey. A survey package and a self-addressed courier envelope were couriered to each of 29 sites. A three week response time was indicated. The project consultants conducted telephone and email follow-up for incomplete data. Unknown supply was estimated by 5 methods. Twenty-eight of 29 sites (97%) completed and returned surveys. Over the past year, respondents reported a total of 5,691 donors (1,550 living and 4,141 cadaveric donors). Including cancellous ground bone, there were 10,729 tissue products produced by the respondent banks. Of these, 71% were produced by accredited banks and 32% were ocular tissues. Total predicted shortfall of allograft tissues was 31,860–66,481 grafts. Through estimating Current supply, and compiling additional qualitative information, this study has provided a snapshot of the current Canadian supply and shortfall of allograft tissue grafts.

Keywords

Allograft Supply Donation Transplantation Tissue 

Abbreviations

AATB

American Association of Tissue Banks

ABA

American Burn Association

ABAA

The Eye Bank Association of America

CCDT

Council for Donation and Transplantation

CIHI

Canadian Institute for Health Information

CJRR

Canadian Joint Replacement Register

CSA

Canadian Standards Association

CTB

Comprehensive Tissue Banks

DMB

Demineralized bone

EB

Eye Banks

EBAA

Eye Bank Association of America

FTEs

Full time equivalents

HMDB

Hospital Morbidity Data Base

ISO

The International Organization for Standardization

MSB

Musculoskeletal Surgical Banks

SBB

Surgical Bone Banks

TSB

Tissue Specific Banks

Notes

Acknowledgements

The authors would like to gratefully acknowledge the significant support and assistance received during the planning, implementation and completion of this study. In particular, we would like to express our sincere appreciation to the surgeons and specialists who responded to surveys as part of this study. These specialists included orthopaedic surgeons, neurosurgeons, cardiovascular surgeons, ophthalmologists, plastic surgeons and Canadian Burn Unit representatives. Through their time and effort, these individuals have made a major contribution.

Another significant level of assistance was received from numerous individuals who gave up their time to meet with the project team. We would like to extend a special thanks to Philip Belitsky, Kim Liss, Maggie Wylie at the Canadian Council for Donation and Transplantation, and Nizar Ladak, Janice Miller, Colleen Zebchuck, Kim Badovinac, and Greg Webster at the Canadian Institute for Health Information (CIHI) for their ongoing input and support for this phase of the study.

References

  1. Brightbill FS (1993) Corneal surgery-theory, technique and tissue, 2nd edn. Mosby, St LouisGoogle Scholar
  2. Canadian Institute for Health Information (2002) Canadian Joint Replacement Registry Report—Total Hip and Total Knee Replacements in Canada, CIHIGoogle Scholar
  3. Canadian Institute for Health Information (2002) Canadian Joint Replacement Registry Supplementary Report—Total Hip and Total Knee Replacements in Canada, CIHIGoogle Scholar
  4. Greenwald SA, Boden SD, Goldberg VM, Khan Y, Laurencin CT, Rosier RN (2002) Bone-Graft Substitutes: Facts, Fictions & Applications. In American Academy of Orthopaedic Surgeons 69th Annual Meeting, Dallas, TexasGoogle Scholar
  5. Hackett K (2001) Tissue Donation, Tissue Bank 2001 Report, HalifaxGoogle Scholar
  6. Lakey JRT, Mirbolooki M, Rogers C, Mohr J (2006) Demand for human allograft tissue in Canada, Cell and Tissue Banking, DOI: 10.1007/s10561-006-9003-2.Google Scholar
  7. Schutt GR, Harringer W, Buddrus R, Haverich A (1990) Heart valve donation from living donors: an underestimated resource? Transplant Proc 29:989–990CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media B.V. 2006

Authors and Affiliations

  • Jonathan R. T. Lakey
    • 1
  • Mohammadreza Mirbolooki
    • 1
  • Christina Rogers
    • 2
  • Jim Mohr
    • 2
  1. 1.Clinical Islet Transplant Program, Department of SurgeryUniversity of AlbertaEdmontonCanada
  2. 2.Canadian Council for Donation and TransplantationEdmontonCanada

Personalised recommendations