Coronary artery calcium scores and cardiovascular risk factors in 31,545 asymptomatic Korean adults

  • Shin Yi Jang
  • Sung Mok Kim
  • Jidong Sung
  • Soo Jin Cho
  • Yeon Hyeon Choe
Original Paper


The aims of this study were to identify the distribution of coronary artery calcium score (CACS) by age group and cardiovascular (CV) risk factors and to evaluate the association between CV risk factors and CACS classification in asymptomatic adults. The study included 31,545 asymptomatic Koreans, over 20 years of age with no previous history of malignancy, proven coronary artery disease, or stroke, who underwent CACS computed tomography at the Health Promotion Center, Samsung Medical Center, between January 2005 and June 2013. Mean (±SD) age was 53.8 (±8.5) years overall, 56.1 (±8.3) in men, and 53.3 (±8.5) in women. They were classified into five groups based on their resting CACS: none (CAC = 0), minimal (0 < CAC ≤ 10), mild (10 < CAC ≤ 100), moderate (100 < CAC ≤ 400), and extensive (400 > CAC). Older age groups exhibited higher CACS values. The proportion of CACS classification in our study was 55.5 % with no CACS, 9.5 % with minimal CACS, 19.8 % with mild CACS, 10.8 % with moderate CACS, and 4.3 % with extensive CACS. Adjusted odds ratios (ORs) were calculated for CV risk factors to determine their association with CACS. When analyzed according to sex, in males, the adjusted OR for CACS increased with the presence of hypertension (HT), diabetes mellitus (DM), obesity, chronic kidney disease, and smoking status. While, in females, the adjusted OR for CACS increased with the presence of HT, DM, and obesity. CV risk factors appear to be significantly associated with CACS in the Korean population.


Cardiovascular risk factors Coronary artery Calcium score CT 


Compliance with ethical standards

Conflict of interest


Supplementary material

10554_2016_892_MOESM1_ESM.pdf (957 kb)
Supplementary material 1 (PDF 957 KB)


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Copyright information

© Springer Science+Business Media Dordrecht 2016

Authors and Affiliations

  • Shin Yi Jang
    • 1
  • Sung Mok Kim
    • 1
    • 2
  • Jidong Sung
    • 3
    • 4
  • Soo Jin Cho
    • 4
  • Yeon Hyeon Choe
    • 1
    • 2
  1. 1.HVSI Imaging Center, Heart Vascular Stroke Institute, Samsung Medical CenterSungkyunkwan University School of MedicineSeoulSouth Korea
  2. 2.Department of Radiology and Center for Imaging Science, Samsung Medical CenterSungkyunkwan University School of MedicineSeoulSouth Korea
  3. 3.Division of Cardiology, Department of Medicine, Samsung Medical CenterSungkyunkwan University School of MedicineSeoulSouth Korea
  4. 4.Department of Medicine, Center for Health Promotion, Samsung Medical CenterSungkyunkwan University School of MedicineSeoulSouth Korea

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