Radiation dose reduction for coronary artery calcium scoring at 320-detector CT with adaptive iterative dose reduction 3D

  • Fuminari Tatsugami
  • Toru Higaki
  • Wataru Fukumoto
  • Yoko Kaichi
  • Chikako Fujioka
  • Masao Kiguchi
  • Hideya Yamamoto
  • Yasuki Kihara
  • Kazuo Awai
Original Paper


To assess the possibility of reducing the radiation dose for coronary artery calcium (CAC) scoring by using adaptive iterative dose reduction 3D (AIDR 3D) on a 320-detector CT scanner. Fifty-four patients underwent routine- and low-dose CT for CAC scoring. Low-dose CT was performed at one-third of the tube current used for routine-dose CT. Routine-dose CT was reconstructed with filtered back projection (FBP) and low-dose CT was reconstructed with AIDR 3D. We compared the calculated Agatston-, volume-, and mass scores of these images. The overall percentage difference in the Agatston-, volume-, and mass scores between routine- and low-dose CT studies was 15.9, 11.6, and 12.6 %, respectively. There were no significant differences in the routine- and low-dose CT studies irrespective of the scoring algorithms applied. The CAC measurements of both imaging modalities were highly correlated with respect to the Agatston- (r = 0.996), volume- (r = 0.996), and mass score (r = 0.997; p < 0.001, all); the Bland–Altman limits of agreement scores were −37.4 to 51.4, −31.2 to 36.4 and −30.3 to 40.9 %, respectively, suggesting that AIDR 3D was a good alternative for FBP. The mean effective radiation dose for routine- and low-dose CT was 2.2 and 0.7 mSv, respectively. The use of AIDR 3D made it possible to reduce the radiation dose by 67 % for CAC scoring without impairing the quantification of coronary calcification.


Coronary artery calcium Iterative reconstruction Dose reduction 320-detector CT scanner 


Conflict of interest

Dr. Kazuo Awai is currently receiving a research grant from Toshiba Medical Systems, Ltd. The remaining authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.


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Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  • Fuminari Tatsugami
    • 1
  • Toru Higaki
    • 1
  • Wataru Fukumoto
    • 1
  • Yoko Kaichi
    • 1
  • Chikako Fujioka
    • 2
  • Masao Kiguchi
    • 2
  • Hideya Yamamoto
    • 3
  • Yasuki Kihara
    • 3
  • Kazuo Awai
    • 1
  1. 1.Department of Diagnostic RadiologyHiroshima UniversityHiroshimaJapan
  2. 2.Department of RadiologyHiroshima UniversityHiroshimaJapan
  3. 3.Department of Cardiovascular MedicineHiroshima UniversityHiroshimaJapan

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