Recoupling of right and left ventricle pump function after surgical ventricle restoration: a cardiac magnetic resonance study

  • Francesco Secchi
  • Marcello Petrini
  • Giovanni Di Leo
  • Francesco Bandera
  • Serenella Castelvecchio
  • Marco Guazzi
  • Lorenzo Menicanti
  • Francesco Sardanelli
Original Paper


To evaluate biventricular pump function after surgical ventricle restoration (SVR) using cardiac magnetic resonance (CMR). We retrospectively studied 39 patients who performed 1.5-T CMR before/after SVR acquiring short-axis ECG-gated cine sequences. End-diastolic, end-systolic, and stroke volume indexed to body surface area (EDVI, ESVI, and SVI), ejection fraction (EF), and their modification after SVR (∆) were obtained for right ventricle (RV) and left ventricle (LV). Wilcoxon signed rank test and Spearman correlation coefficient were used; EF reproducibility was estimated. Median LVEF increased from 24 % [interquartile range (IQR) 19–31 %] before SVR to 34 % (IQR 29–43 %) after SVR (P < 0.001). Median RVEF remained unchanged from 58 % (IQR 48–66 %) before SVR to 57 % (IR 46–64 %) after SVR (P = 0.743). The correlation between LVEF and RVEF was not significant before SVR (r = 0.182; P = 0.266) but significant after SVR (r = 0.445; P = 0.005). The ∆RVEF was positively correlated with ∆LVEF (r = 0.558; P < 0.001). ∆RVSVI was positively correlated with ∆LVSVI (r = 0.502; P = 0.001). LVEF reproducibility before SVR was 97 % for both intra- and inter-reader reproducibility; RVEF reproducibility was 96 and 93 %, respectively. SVR improved LV function without apparent impact on RV function. After SVR the two ventricles showed a functional recoupling. Reproducibility of CMR EF was excellent for both ventricles.


Cardiac magnetic resonance Intra- and inter-reader reproducibility Left ventricle Right ventricle Surgical ventricle restoration Ventricular recoupling 


Conflict of interest



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Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  • Francesco Secchi
    • 1
  • Marcello Petrini
    • 2
  • Giovanni Di Leo
    • 1
  • Francesco Bandera
    • 3
  • Serenella Castelvecchio
    • 4
  • Marco Guazzi
    • 3
    • 5
  • Lorenzo Menicanti
    • 4
  • Francesco Sardanelli
    • 1
    • 5
  1. 1.Unità di RadiologiaIRCCS Policlinico San DonatoSan Donato MilaneseItaly
  2. 2.Scuola di Specializzazione in RadiodiagnosticaUniversità degli Studi di MilanoMilanItaly
  3. 3.Heart Failure UnitIRCCS Policlinico San DonatoSan Donato MilaneseItaly
  4. 4.Unità di CardiochirurgiaIRCCS Policlinico San DonatoSan Donato MilaneseItaly
  5. 5.Dipartimento di Scienze Biomediche per la SaluteUniversità degli Studi di MilanoMilanItaly

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