Quantification of stenotic mitral valve area and diagnostic accuracy of mitral stenosis by dual-source computed tomography in patients with atrial fibrillation: comparison with cardiovascular magnetic resonance and transthoracic echocardiography

  • Song Soo Kim
  • Sung Min Ko
  • Meong Gun Song
  • Hyun Kun Chee
  • Jun Suk Kim
  • Hweung Kon Hwang
  • Jae-Hwan Lee
Original Paper


This study aimed to evaluate the utility of dual-source computed tomography (DSCT) for quantification of the mitral valve area (MVA) in patients with atrial fibrillation (AF) and mitral stenosis (MS) and to compare the results of DSCT with those of cardiovascular magnetic resonance (CMR) and transthoracic echocardiography (TTE). One hundred-two patients with AF and MS who had undergone electrocardiography-gated DSCT, TTE and CMR prior to operation were retrospectively enrolled. The MVA was planimetrically determined by DSCT, CMR, and TTE, as well as by Doppler TTE using the pressure half-time method (TTE–PHT). Agreement, relationship between measurements, and the highest accuracy were evaluated using Bland–Altman, Pearson correlation, and receiver operating characteristic analyses. The MVA on DSCT (mean, 1.27 ± 0.27 cm2) was significantly larger than that on CMR (1.15 ± 0.28 cm2, P < 0.05), TTE-planimetry and TTE–PHT (1.16 ± 0.28 and 1.07 ± 0.30 cm2, respectively; P < 0.05). TTE-planimetry had better correlation with planimetry on DSCT and CMR (r = 0.65 and 0.67, respectively; P < 0.05) than TTE–PHT (r = 0.51 and 0.55, respectively; P < 0.05). Using an MVA of 1.0 cm2 on TTE-planimetry and TTE–PHT as the reference, the optimal thresholds for detecting severe MS on DSCT was 1.19 cm2. The planimetry of the MVA measured by DSCT may be a reliable, alternative method for the quantification of MS in patients with AF.


Mitral valve Mitral valve stenosis Atrial fibrillation Dual-source CT Echocardiography 



Atrial fibrillation


Coronary computed tomography angiography


Cardiovascular magnetic resonance


Dual-source computed tomography


Pressure half-time


Mitral stenosis


Mitral valve area


Mitral valvuloplasty


Transthoracic echocardiography


Conflict of interest



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Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • Song Soo Kim
    • 1
  • Sung Min Ko
    • 2
  • Meong Gun Song
    • 3
  • Hyun Kun Chee
    • 3
  • Jun Suk Kim
    • 3
  • Hweung Kon Hwang
    • 4
  • Jae-Hwan Lee
    • 5
  1. 1.Department of Radiology, Chungnam National University HospitalChungnam National University School of MedicineDaejeonKorea
  2. 2.Departments of Radiology, Research Institute of Medical Science, Konkuk University Medical CenterKonkuk University School of MedicineSeoulKorea
  3. 3.Department of Thoracic Surgery, Konkuk University HospitalKonkuk University School of MedicineSeoulKorea
  4. 4.Department of Cardiology, Konkuk University HospitalKonkuk University School of MedicineSeoulKorea
  5. 5.Division of Cardiology, Department of Internal Medicine, Chungnam National University HospitalChungnam National University School of MedicineDaejeonKorea

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