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Prevalence and pattern of abnormal myocardial perfusion in patients with isolated coronary artery ectasia: study by 99mTc-sestamibi radionuclide scintigraphy

  • Ahmed M. Ismail
  • Mona Rayan
  • Amr Adel
  • Salah Demerdash
  • Mohamed Atef
  • Mohamed Abdallah
  • Wail Nammas
Original Paper

Abstract

We explored the prevalence and pattern of abnormal myocardial perfusion in patients with isolated coronary artery ectasia (CAE), as demonstrated by 99mTc-sestamibi scintigraphy. Prospectively, we enrolled 35 patients with angiographically documented CAE and no significant coronary obstruction, who underwent elective coronary angiography. Patients underwent Stress-rest 99mTc-sestamibi scintigraphy within 4 days of coronary angiography. They were divided into 2 groups: group I: with normal perfusion scan; and group II: with reversible perfusion defects. The mean age was 49.6 ± 6.9 years; 34 (97.1 %) were males. Seventy-nine (75.2 %) arteries were affected by CAE. Among 79 arteries affected by CAE, affection was diffuse in 37 (46.8 %). Thirteen (37.1 %) patients had normal perfusion scan (group I), whereas 22 (62.9 %) had reversible perfusion defects (group II). Among 22 patients with reversible perfusion defects, 20 (90.9 %) had mild and 2 (9.1 %) had moderate ischemia. Among 49 myocardial segments with reversible perfusion defects, 22 (44.9 %) were basal, 18 (36.7 %) mid-, and 9 (18.4 %) apical segments. Diffuse CAE was significantly more prevalent in group II versus group I, in all 3 major coronary arteries (p < 0.05 for all). In patients with isolated CAE who underwent elective coronary angiography, reversible perfusion defects demonstrated by 99mTc-sestamibi scintigraphy were rather prevalent, mostly mild, more likely to affect the basal and mid-segments of the myocardium, and more frequently associated with diffuse ectasia.

Keywords

Coronary artery ectasia Myocardial perfusion 99mTc-sestamibi scintigraphy 

Notes

Conflict of interest

All authors have no conflict of interest to declare.

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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Ahmed M. Ismail
    • 1
  • Mona Rayan
    • 1
  • Amr Adel
    • 1
  • Salah Demerdash
    • 1
  • Mohamed Atef
    • 1
  • Mohamed Abdallah
    • 1
  • Wail Nammas
    • 1
  1. 1.Cardiology Department, Faculty of MedicineAin Shams UniversityAbbassia, CairoEgypt

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