Prospective ECG-gated 320 row detector computed tomography: implications for CT angiography and perfusion imaging
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Cardiac multidetector computed tomography has evolved from early four detector systems that first demonstrated the feasibility of non-invasive angiography to today’s wide-area detector computed tomography systems, such as 320-row detector computed tomography. As detector arrays have widened, there have been great improvements in image quality that have improved test accuracy. In addition, wider detector arrays have allowed for the application of prospective ECG-gating for CT angiography, although the current 64-row detector systems have some limitations. 320-row detector computed tomography with full cardiac coverage allows for cardiac imaging in a single heart beat. This technology has realized some of the great advantages provided by full cardiac coverage in regards to image quality (elimination of step artifacts and variation in contrast enhancement), patient safety (reductions in overall radiation and contrast dose), and the prospects for combined CT angiography and myocardial perfusion imaging are very promising. We will review the technical aspects of 320-row detector computed tomography and their implications for coronary angiography and perfusion imaging.
KeywordsMyocardial perfusion Non-invasive angiography Wide-area computed tomography 320-Row detector computed tomography Dynamic volume computed tomography Prospective ECG-gating
Donald W. Reynolds Foundation, Las Vegas, Nevada, American College of Cardiology Foundation; PJ Schafer Memorial Research Grant, Timonium, MD; Toshiba American Medical Systems, Tufton, CA; Astellas Pharma US, Inc., Deerfield, IL.
Dr. George, Dr. Lima and Dr. Lardo are, in part, funded by a research grant from Toshiba American Medical Systems, Inc. Dr. George and Dr. Lima is, in part funded by a research grant from Astellas Pharma US, Inc. Dr. Lardo and Dr. George have received speaker’s fees from Toshiba American Medical Systems, Inc. The terms of these arrangements are being managed by Johns Hopkins University in accordance with its conflict of interest policies.
American College of Cardiology Foundation Career Development Award, Donald W. Reynolds Foundation Clinical Cardiovascular Research Center Award, PJ Schafer Memorial Research Grant, Toshiba Medical Systems Corporation, Astellas Pharma, Inc.
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