Left ventricular myocardial volumes measured during arterial and delayed phases of multidetector row computed tomography: a study on intra- and interobserver variability
To compare and correlate left ventricular (LV) myocardial volumes obtained using arterial and delayed phases of multidetector row computed tomography (CT) and evaluate their intra- and interobserver variation. Two observers evaluated the arterial- and delayed-phase serial short-axis images of 45 healthy volunteers. Intra- and interobserver variations in LV myocardial volumes were correlated with four factors—myocardial volume, contrast-volume-to-body-weight ratio, and contrast-to-noise ratios in the arterial and delayed phases. Variations in the apex, mid-ventricle, and base were compared. Intra- and interobserver analyzes revealed no statistical difference and good correlation. Intra- and interobserver variations were within 5 and 10%, respectively, and were independent of the four factors. Variations were the highest at the apex. LV myocardial volumes measured using arterial- and delayed-phase cardiac CT exhibit no significant difference and good correlation. Intra- and interobserver variations are both clinically acceptable, and the apex contributes most to these variations.
KeywordsMultidetector computed tomography Myocardial infarction Myocardial viability Myocardial volume Coronary heart disease
- 5.Sato A, Hiroe M, Nozato T et al (2008) Early validation study of 64-slice multidetector computed tomography for the assessment of myocardial viability and the prediction of left ventricular remodelling after acute myocardial infarction. Eur Heart J 29(4):490–498. doi: 10.1093/eurheartj/ehm630 PubMedCrossRefGoogle Scholar
- 7.Lardo AC, Corderiro MA, Silva C et al (2006) Contrast-enhanced multidetector computed tomography viability imaging after myocardial infarction: characterization of myocyte death, microvascular obstruction, and chronic scar. Circulation 113(3):394–404. doi: 10.1161/CIRCULATIONAHA.105.521450 PubMedCrossRefGoogle Scholar
- 9.Habis M, Capderou A, Ghostine S et al (2007) Acute myocardial infarction early viability assessment by 64-slice computed tomography immediately after coronary angiography: comparison with low-dose dobutamine echocardiography. J Am Coll Cardiol 49(11):1178–1185. doi: 10.1016/j.jacc.2006.12.032 PubMedCrossRefGoogle Scholar
- 15.Lee T, Tsai IC, Fu YC et al (2006) Using multidetector-row CT in neonates with complex congenital heart disease to replace diagnostic cardiac catheterization for anatomical investigation: initial experiences in technical and clinical feasibility. Pediatr Radiol 36(12):1273–1282. doi: 10.1007/s00247-006-0315-y PubMedCrossRefGoogle Scholar
- 16.Weisstein EW (2008) Bonferroni correction from MathWorld–a Wolfram Web Resource. Available at http://mathworld.wolfram.com/BonferroniCorrection. html Accessed on 12 December 2008