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Assessment of left ventricular function: comparison of cardiac multidetector-row computed tomography with two-dimension standard echocardiography for assessment of left ventricular function

  • Darpan Bansal
  • Robin M. Singh
  • Mrinalini Sarkar
  • Ravi Sureddi
  • Kelly C. Mcbreen
  • Timothy Griffis
  • Anjan Sinha
  • Jawahar L. Mehta
Original Paper

Abstract

Objective

To compare global Left Ventricular (LV) systolic function assessment by 16-detector row Computed Tomography (MDCT) with Two-Dimensional Standard Echocardiography (2DSE) in a routine cardiology practice setting and to ascertain the degree of correlation between LV volumes and measurements obtained by 2DSE with those measured by MDCT.

Methods

In 52 patients with suspected coronary artery disease, a contrast enhanced MDCT study was performed using retrospective gating without dose modulation for better endocardial delineation. Eight phases of the cardiac cycle were analyzed to identify the end-diastolic and end-systolic phases. 2DSE was performed on the same day. Left ventricular systolic and diastolic volumes and ejection fraction were calculated in 4-chamber, 2-chamber and biplane (average of the two) views. Endocardial tracing was used to measure ventricular volumes by area length method for CT and Simpson’s method for echocardiography.

Results

On MDCT, mean LV ejection fraction (LVEF) in 4-chamber, 2-chamber and biplane views were 58.4 ± 12, 59.3 ± 12 and 59.7 ± 12% respectively. On 2DSE, mean LVEF in 4-chamber, 2-chamber and biplane views were 58 ± 14, 57 ± 16 and 58 ± 13% respectively. LVEF correlated best using the biplane views (r = 0.59 and P < 0.01) compared to 2-chamber (r = 0.57 and P < 0.01) and 4-chamber views (r = 0.32 and P = 0.02). Biplane measurement by these two techniques correlated well for LV volumes in both diastole (r = 0.69 and P < 0.01) and systole (r = 0.73 and P < 0.01), although MDCT consistently gave higher values.

Conclusions

MDCT can be a useful tool to measure LVEF while patients are undergoing CT coronary angiography.

Keywords

Computed tomography Echocardiography Left ventricular ejection fraction 

Abbreviations

Bip

Biplane

CAD

Coronary artery disease

CMRI

Cardiac magnetic resonance imaging

LV

Left ventricle

LVEF

Left ventricular ejection fraction

LVEDV

Left ventricular end-diastolic volume

LVESV

Left ventricular end-systolic volume

MDCT

Multi-detector row computed tomography

SV

Stroke volume

2D

Two dimensional

2DSE

Two dimensional standard echocardiography

4c

Four chamber

2c

Two chamber

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Copyright information

© Springer Science+Business Media B.V. 2007

Authors and Affiliations

  • Darpan Bansal
    • 1
  • Robin M. Singh
    • 1
  • Mrinalini Sarkar
    • 1
  • Ravi Sureddi
    • 1
  • Kelly C. Mcbreen
    • 1
  • Timothy Griffis
    • 1
  • Anjan Sinha
    • 1
  • Jawahar L. Mehta
    • 1
  1. 1.Division of Cardiovascular Medicine, Arkansas Cardiology and the Central Arkansas Veterans Healthcare SystemUniversity of Arkansas for Medical SciencesLittle RockUSA

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