Cardiac MRI documented left ventricular thrombus complicating acute takotsubo syndrome: an uncommon dilemma

  • Veerpal Singh
  • Tom Mayer
  • John Salanitri
  • Michael H. Salinger


Transient left ventricular apical hypokinesis results in a typical ampullary shape and has been described as Takotsubo cardiomyopathy (TCM). We report a case of TCM with the rare complication of left ventricular thrombus formation. Cardiac magnetic resonance imaging aided the diagnosis by characterizing the non-enhancing mass and evaluating the surrounding myocardium for scarring.


Takotsubo cardiomyopathy Left ventricular thrombus Cardiac MRI 



Cardiac MRI


Myocardial Infarction


Takotsubo Cardiomyopathy


Transthoracic Echocardiography


  1. 1.
    Bybee KA, Kara T, Prasad A et al (2004) Systematic review: transient left ventricular apical ballooning: a syndrome that mimics ST-segment elevation myocardial infarction. Ann Intern Med 141:858–865PubMedGoogle Scholar
  2. 2.
    Sharkey SW, Lesser JR, Aenovich AG et al (2005) Acute and reversible cardiomyopathy provoked by stress in women from the United States. Circulation 111:473–479CrossRefGoogle Scholar
  3. 3.
    Kurisu S, Inoue I, Kawagoe T et al (2003) Left ventricular apical thrombus formation in a patient with suspected Tako-Tsubo-like left ventricular dysfunction. Circ J 67:556–558PubMedCrossRefGoogle Scholar
  4. 4.
    Wittstein IS, Thiemann DR, Lima JA et al (2005) Neurohumoral features of myocardial stunning due to sudden emotional stress. N Engl J Med 352(6):539–48PubMedCrossRefGoogle Scholar
  5. 5.
    Sasaki N, Kinugawa T, Yamawaki M, et al (2004) Transient left ventricular apical ballooning in a patient with bicuspid aortic valve created a left ventricular thrombus leading to acute renal infarction. Circ J 68:1081–1083PubMedCrossRefGoogle Scholar
  6. 6.
    Mollet NR, Dymarkowski S, Volders W et al (2002) Visualization of ventricular thrombi with contrast-enhanced magnetic resonance imaging in patients with ischemic heart disease. Circulation 106:2873–2876PubMedCrossRefGoogle Scholar
  7. 7.
    Fritz J, Wittstein IS, Lima JA, et al (2005) Transient left ventricular apical ballooning: magnetic resonance imaging evaluation. J Comput Assist Tomogr 29(1):34–36PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Veerpal Singh
    • 1
  • Tom Mayer
    • 1
  • John Salanitri
    • 1
  • Michael H. Salinger
    • 1
  1. 1.Division of CardiologyEvanston Northwestern HealthcareEvanstonUS

Personalised recommendations