Trends in published meta-analyses in cancer research, 2008–2013
In order to capture trends in the contribution of epidemiology to cancer research, we describe an online meta-analysis database resource for cancer clinical and population research and illustrate trends and descriptive detail of cancer meta-analyses from 2008 through 2013. A total of 4,686 cancer meta-analyses met our inclusion criteria. During this 6-year period, a fivefold increase was observed in the yearly number of meta-analyses. Fifty-six percent of meta-analyses concerned observational studies, mostly of cancer risk, more than half of which were genetic studies. The major cancer sites were breast, colorectal, and digestive. This online database for Cancer Genomics and Epidemiology Navigator will be continuously updated to allow investigators to quickly navigate the meta-analyses emerging from cancer epidemiology studies and cancer clinical trials.
KeywordsMeta-analysis Database Epidemiology Clinical trials
Ximena V. Qadir conducted the analyses and drafted the manuscript. Mindy Clyne conducted additional data analyses and prepared Methods section of the text. Tram Kim Lam prepared Discussion section of the text. Muin J. Khoury drafted Discussion section of the text and revised it for important intellectual content and contribution to the field of Epidemiology. Sheri D. Schully contributed significantly to the design of the project and supervised field activities. Significant effort and contribution was made from all authors.
Compliance with ethical standards
Conflict of interest
Authors have no conflict of interests to disclose.
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