Characteristics, rates, and trends of melanoma incidence among Hispanics in the USA
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The purpose of this study is to describe the epidemiology of melanoma among Hispanics using data that cover nearly 100 % of the US population.
The study used population-based cancer incidence data from the National Program of Cancer Registries and the Surveillance, Epidemiology and End Results Program to examine melanoma incidence rates and trends among Hispanics by sex, age, race, histology, anatomic location, stage, and tumor thickness.
From 2008 to 2012, 6,623 cases of melanoma were diagnosed among Hispanics. Rates were higher among males (4.6) than among females (4.0), but females younger than age 55 had higher rates than males. The most common histologic subtype was superficial spreading melanoma (23 %). Melanomas with poorer outcomes, such as nodular (NM) and acral lentiginous melanoma (ALM), were more common among males. Hispanic females had the highest proportion of melanoma on the lower limb and hip (33.7 %), while Hispanic males had the highest proportion on the trunk (29.9 %). Incidence rates for later-stage diagnosis and thicker tumors were significantly higher among Hispanic men than among women. Incidence rates decreased significantly during 2003–2012 (AAPC = −1.4).
Clinicians and public health practitioners will need to reach the growing Hispanic population in the USA with strategies for primary prevention and early diagnosis of melanoma. Results suggest Hispanics and providers need education to increase awareness about the characteristics of melanoma among Hispanics, including types that occur on non-sun-exposed areas (ALM and NM). Skin cancer prevention and awareness interventions targeting Hispanics should be culturally relevant.
KeywordsMelanoma incidence rates Melanoma incidence trends Melanoma histology Melanoma stage Anatomic location of melanoma Hispanics
The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.
Compliance with ethical standards
Conflict of interest
The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- 1.U.S. Cancer Statistics Working Group (2015) United States Cancer Statistics: 1999–2012 Incidence and Mortality Web-based Report. Centers for Disease Control and Prevention, U.S. Dept of Health and Human Services and National Cancer Institute, National Institutes of Health. http://www.cdc.gov/uscs. Accessed 1 Sept 2015
- 2.U.S. Department of Health and Human Services (2014) The Surgeon General’s call to action to prevent skin cancer. Dept of Health and Human Services, Office of the Surgeon General, Washington, DCGoogle Scholar
- 3.Hu S, Parmet Y, Allen G, Parker DF, Ma F, Rouhani P, Kirsner RS (2009) Disparity in melanoma: a trend analysis of melanoma incidence and stage at diagnosis among whites, Hispanics, and blacks in Florida. Arch Dermatol 145(12):1369–1374. doi: 10.1001/archdermatol.2009.302 CrossRefPubMedGoogle Scholar
- 9.Pollitt RA, Clarke CA, Swetter SM, Peng DH, Zadnick J, Cockburn M (2011) The expanding melanoma burden in California Hispanics: importance of socioeconomic distribution, histologic subtype, and anatomic location. Cancer 117(1):152–161. doi: 10.1002/cncr.25355 CrossRefPubMedPubMedCentralGoogle Scholar
- 12.Wu XC, Eide MJ, King J, Saraiya M, Huang Y, Wiggins C, Barnholtz-Sloan JS, Martin N, Cokkinides V, Miller J, Patel P, Ekwueme DU, Kim J (2011) Racial and ethnic variations in incidence and survival of cutaneous melanoma in the United States, 1999–2006. J Am Acad Dermatol 65(5 Suppl 1):S26–S37. doi: 10.1016/j.jaad.2011.05.034 PubMedGoogle Scholar
- 13.Agbai ON, Buster K, Sanchez M, Hernandez C, Kundu RV, Chiu M, Roberts WE, Draelos ZD, Bhushan R, Taylor SC, Lim HW (2014) Skin cancer and photoprotection in people of color: a review and recommendations for physicians and the public. J Am Acad Dermatol 70(4):748–762. doi: 10.1016/j.jaad.2013.11.038 CrossRefPubMedGoogle Scholar
- 19.Andreeva VA, Unger JB, Yaroch AL, Cockburn MG, Baezconde-Garbanati L, Reynolds KD (2009) Acculturation and sun-safe behaviors among US Latinos: findings from the 2005 Health Information National Trends Survey. Am J Public Health 99(4):734–741. doi: 10.2105/ajph.2007.122796 CrossRefPubMedPubMedCentralGoogle Scholar
- 21.Andreeva VA, Cockburn MG (2011) Cutaneous melanoma and other skin cancer screening among Hispanics in the United States: a review of the evidence, disparities, and need for expanding the intervention and research agendas. Arch Dermatol 147(6):743–745. doi: 10.1001/archdermatol.2011.140 CrossRefPubMedGoogle Scholar
- 24.US Census Bureau (2014) Table 16. Projected rates for components of change by race and Hispanic origin for the United States: 2015 to 2060 (NP2014-T16) US Census Bureau, Population Division http://www.census.gov/population/projections/files/summary/NP2014-T16.xls Accessed 12 Feb 2014
- 25.United States Cancer Statistics (USCS) Technical notes: USCS publication criteria. US Department of Health and Human Services, Centers for Disease Control and Prevention, Division of Cancer Prevention and Control. http://www.cdc.gov/cancer/npcr/uscs/technical_notes/criteria.htm. Accessed 29 April 2015
- 26.National Cancer Institute Surveillance, Epidemiology and End Results Program Website. US Dept of Health and Human Services, National Institutes of Health, National Cancer Institute. http://seer.cancer.gov/. Accessed 26 May 2015
- 27.National Program of Cancer Registries National Program of Cancer Registries Website. US Dept of Health and Human Services, Centers for Disease Control and Prevention. http://www.cdc.gov/cancer/npcr/. Accessed 26 May 2015
- 28.Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) SEER*Stat Database: Incidence—SEER 18 Regs Research Data + Hurricane Katrina Impacted Louisiana Cases, Nov 2014 Sub (2000–2012) <Katrina/Rita Population Adjustment>—Linked To County Attributes—Total U.S., 1969–2013 Counties, National Cancer Institute, Division of Cancer Control and Population Sciences, Surveillance Research Program, Surveillance Systems Branch, released April 2015, based on the November 2014 submission
- 29.NAACCR Race and Ethnicity Work Group (2011) NAACCR Guideline for enhancing Hispanic/Latino identification: revised NAACCR Hispanic/Latino identification algorithm [NHIA v2.2.1]. North American Association of Central Cancer Registries, SpringfieldGoogle Scholar
- 30.Collaborative Staging Task Force of the American Joint Committee on Cancer (2004) Collaborative Staging Manual and Coding Instructions, version 01.03.00Google Scholar
- 31.Centers for Disease Control and Prevention’s Division of Cancer Prevention and Control, National Institutes of Health’s National Cancer Institute (2015) United States Cancer Statistics Restricted Access Data Set Data Dictionary and Data Standards, 2014 November data submission. US Dept of Health and Human Services, Centers for Disease Control and Prevention, Division of Cancer Prevention and Control, Cancer Surveillance Branch, Atlanta, GA, and National Institutes of Health, National Cancer Institute, Surveillance Research Program, Bethesda, MDGoogle Scholar
- 32.Surveillance Research Program NCI SEER Stat Fact Sheets: Melanoma of the Skin. US Department of Health and Human Services, National Institutes of Health, National Cancer Institute. http://seer.cancer.gov/statfacts/html/melan.html. Accessed 23 April 2015
- 33.Weir HK, Marrett LD, Cokkinides V, Barnholtz-Sloan J, Patel P, Tai E, Jemal A, Li J, Kim J, Ekwueme DU (2011) Melanoma in adolescents and young adults (ages 15–39 years): United States, 1999–2006. J Am Acad Dermatol 65(5 suppl 1):S38–S49. doi: 10.1016/j.jaad.2011.04.038 PubMedPubMedCentralGoogle Scholar
- 34.Populo H, Boaventura P, Vinagre J, Batista R, Mendes A, Caldas R, Pardal J, Azevedo F, Honavar M, Guimaraes I, Manuel Lopes J, Sobrinho-Simoes M, Soares P (2014) TERT promoter mutations in skin cancer: the effects of sun exposure and X-irradiation. J Invest Dermatol 134(8):2251–2257. doi: 10.1038/jid.2014.163 CrossRefPubMedGoogle Scholar
- 37.United States Cancer Statistics: 1999–2012 Mortality, WONDER Online Database. United States Department of Health and Human Services, Centers for Disease Control and Prevention (2015). http://wonder.cdc.gov/CancerMort-v2012.html Accessed 17 Nov 2015
- 41.Lachiewicz AM, Berwick M, Wiggins CL, Thomas NE (2008) Survival differences between patients with scalp or neck melanoma and those with melanoma of other sites in the Surveillance, Epidemiology, and End Results (SEER) program. Arch Dermatol 144(4):515–521. doi: 10.1001/archderm.144.4.515 CrossRefPubMedGoogle Scholar
- 43.Chang YM, Barrett JH, Bishop DT, Armstrong BK, Bataille V, Bergman W, Berwick M, Bracci PM, Elwood JM, Ernstoff MS, Gallagher RP, Green AC, Gruis NA, Holly EA, Ingvar C, Kanetsky PA, Karagas MR, Lee TK, Le Marchand L, Mackie RM, Olsson H, Osterlind A, Rebbeck TR, Sasieni P, Siskind V, Swerdlow AJ, Titus-Ernstoff L, Zens MS, Newton-Bishop JA (2009) Sun exposure and melanoma risk at different latitudes: a pooled analysis of 5,700 cases and 7,216 controls. Int J Epidemiol 38(3):814–830. doi: 10.1093/ije/dyp166 CrossRefPubMedPubMedCentralGoogle Scholar
- 47.Hodis E, Watson IR, Kryukov GV, Arold ST, Imielinski M, Theurillat JP, Nickerson E, Auclair D, Li L, Place C, Dicara D, Ramos AH, Lawrence MS, Cibulskis K, Sivachenko A, Voet D, Saksena G, Stransky N, Onofrio RC, Winckler W, Ardlie K, Wagle N, Wargo J, Chong K, Morton DL, Stemke-Hale K, Chen G, Noble M, Meyerson M, Ladbury JE, Davies MA, Gershenwald JE, Wagner SN, Hoon DS, Schadendorf D, Lander ES, Gabriel SB, Getz G, Garraway LA, Chin L (2012) A landscape of driver mutations in melanoma. Cell 150(2):251–263. doi: 10.1016/j.cell.2012.06.024 CrossRefPubMedPubMedCentralGoogle Scholar
- 48.Community Preventive Services Task Force (2013) Preventing skin cancer: interventions in outdoor occupational settings. The Guide to Community Preventive Services website. http://www.thecommunityguide.org/cancer/skin/education-policy/outdooroccupations.html. Accessed 9 Dec 2013
- 49.U.S. Department of Labor (2005) Findings from the National Agricultural Workers Survey (NAWS) 2001–2002. A Demographic and Employment Profile of United States Farm Workers. Research Report, No. 9. U.S. Dept of Labor, Washington, DCGoogle Scholar
- 56.Centers for Disease Control and Prevention (2015) 1991–2013 high school youth risk behavior survey data. US Dept of Health and Human Services, Centers for Disease Control and Prevention. http://nccd.cdc.gov/youthonline/App/Default.aspx. Accessed 12 May 2015
- 59.U.S. Preventive Services Task Force (2012) Behavioral counseling to prevent skin cancer: U.S. Preventive Services Task Force Recommendation Statement website. http://www.uspreventiveservicestaskforce.org/uspstf11/skincancouns/skincancounsrs.htm. Accessed 16 May 2013
- 62.Coups EJ, Stapleton JL, Manne SL, Hudson SV, Medina-Forrester A, Rosenberg SA, Gordon M, Tatum KS, Robinson JK, Natale-Pereira A, Goydos JS (2014) Psychosocial correlates of sun protection behaviors among U.S. Hispanic adults. J Behav Med 37(6):1082–1090. doi: 10.1007/s10865-014-9558-5 CrossRefPubMedPubMedCentralGoogle Scholar
- 64.Hu S, Kirsner RS (2011) Practice gaps—suboptimal skin cancer screening and delayed melanoma diagnosis in Hispanics: comment on “cutaneous melanoma and other skin cancer screening among Hispanics in the United States”. Arch Dermatol 147(6):745–746. doi: 10.1001/archdermatol.2011.141 CrossRefPubMedGoogle Scholar
- 65.Coups EJ, Stapleton JL, Hudson SV, Medina-Forrester A, Rosenberg SA, Gordon MA, Natale-Pereira A, Goydos JS (2013) Linguistic acculturation and skin cancer-related behaviors among Hispanics in the southern and western United States. JAMA Dermatol 149(6):679–686. doi: 10.1001/jamadermatol.2013.745 CrossRefPubMedPubMedCentralGoogle Scholar
- 66.Coups EJ, Stapleton JL, Hudson SV, Medina-Forrester A, Natale-Pereira A, Goydos JS (2012) Sun protection and exposure behaviors among Hispanic adults in the United States: differences according to acculturation and among Hispanic subgroups. BMC Public Health 12:985. doi: 10.1186/1471-2458-12-985 CrossRefPubMedPubMedCentralGoogle Scholar
- 67.Dominguez K, Penman-Aguilar A, Chang MH, Moonesinghe R, Castellanos T, Rodriguez-Lainz A, Schieber R (2015) Vital signs: leading causes of death, prevalence of diseases and risk factors, and use of health services among Hispanics in the United States—2009–2013. MMWR Morb Mortal Wkly Rep 64(17):469–478PubMedGoogle Scholar
- 68.Pinheiro PS, Sherman R, Fleming LE, Gomez-Marin O, Huang Y, Lee DJ, Penedo FJ (2009) Validation of ethnicity in cancer data: Which Hispanics are we misclassifying? J Regist Manag 36(2):42–46Google Scholar