We thank Dr. Fornalski and the other co-authors from the SARI organization for their interest in our study of the lung cancer risk attributed to radon in Swedish dwellings. Their message is that “…excess risk of lung cancer due to low concentrations of radon has been neither empirically detected nor theoretically demonstrated, while the opposite has in fact been supported by voluminous evidence.”
We respectfully disagree. While our paper is not an original epidemiological study on the association between lung cancer and low-level radon in Swedish dwellings, such studies have been performed [1] and show results completely compatible with the results of previous multicenter studies or meta-analyses in Europe and the USA [2–4] and large studies from China [5]. In our study we used the exposure–response (ER) function found by Darby et al. [2], since the European results were considered most representative of the Swedish situation. Importantly, there was no indication of a threshold, but the risk of lung cancer increased with a linear trend, and the estimated ER was similar for residential radon levels below 200 Bq/m3 [2].
These studies were also recently reviewed by the International Agency for Research on Cancer (IARC), and the conclusion was that the results of studies of lung cancer after residential radon exposure are compatible with the risk estimate in studies of miners with much higher exposure [6].
We also thank Dr. Fornalski and coauthors for making us aware that there exists a special organization, SARI [7], which is of the opinion that low-risk radiation is not harmful and even could be used to treat cancer and Alzheimer’s disease (!?).
References
Pershagen G, Åkerblom G, Axelsson O (1994) Residential radon exposure and lung cancer in Sweden. N Engl J Med 330:159–164
Darby S, Hill D, Auvinen A, Barros-Dios JM, Baysson HFB, Deo H, Falk R, Forastiere F, Hakama M, Heid I, Kreienbrock L, Kreuzer M, Lagarde F, Makelainen I, Muirhead C, Oberaigner WGP, Ruano-Ravina A, Ruosteenoja E, Rosario AS, Tirmache M, Tomasek L, Whitley E, Wichmann HE, Doll R (2005) Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case–control studies. Br Med J 330(7485):223
Krewski D, Lubin JH, Zielinski JM et al (2005) Residential radon and risk of lung cancer: a combined analysis of 7 North American case–control studies. Epidemiology 16:137–145
Krewski D, Lubin JH, Zielinski JM et al (2006) A combined analysis of North American case–control studies of residential radon and lung cancer. J Toxicol Environ Health A 69:533–597
Zhang Z-L, Sun J, Dong JY et al (2012) Residential radon and lung cancer risk: an updated meta-analysis of case–control studies. Asian Pac J Cancer Prev 13:2459–2465
International Agency for Research on Cancer (IARC) (2012) Radiation. IARC Monographs 100D. IARC, Lyon, France
Doss M et al (2015) No reason to fear low-dose radiation. Go Nuclear, January 2015. http://go-nuclear.org/sports/item/785-no-reason-to-fear-low-dose-radiation-sari
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Barregard, L., Andersson, E.M. & Axelsson, G. Response to Fornalski et al.. Cancer Causes Control 26, 1519 (2015). https://doi.org/10.1007/s10552-015-0639-8
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DOI: https://doi.org/10.1007/s10552-015-0639-8