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Cancer Causes & Control

, Volume 25, Issue 8, pp 1063–1073 | Cite as

Socioeconomic status and epithelial ovarian cancer survival in Sweden

  • Elisabete Weiderpass
  • Jin-Kyoung Oh
  • Sara Algeri
  • Rino Bellocco
Original paper

Abstract

Purpose

To investigate socioeconomic disparities in epithelial ovarian cancer (EOC) survival in Sweden.

Methods

A cohort of 635 women with invasive EOC who participated in a nationwide population-based case–control study was included in the present population-based prospective study. Women were diagnosed with EOC between 1993 and 1995. Mortality until 31 December 2007 was determined through linkage with the Swedish Cause of Death Registry. Clinical data (tumor stage and tumor differentiation) and indicators of socioeconomic status (SES, education level, and annual individual disposable income) were retrieved from medical records and a nationwide database, respectively. The Cox proportional hazards regression model and the Laplace regression model were used to estimate the effect of clinical factors and SES on EOC survival.

Results

The main factors associated with EOC survival were tumor stage and tumor differentiation: women with stage II, III, and IV tumors had a greater mortality risk than those with stage I tumors [hazard ratio (HR) 2.65, 95 % confidence interval (CI) 1.73–4.07; HR 6.69, 95 % CI 4.85–9.22; HR 12.84, 95 % CI 8.90–18.66, respectively]. After adjustment for these tumor characteristics, no clear association remained between our indicators of SES and EOC survival, but better survival was observed among women with stage IV tumors and a higher income level, and among women with poorly differentiated tumors and a higher education level. Nevertheless, there was no evidence of extended survival among women with higher compared to lower SES.

Conclusions

Our study provides no convincing evidence of an association between SES and EOC survival in Sweden.

Keywords

Ovarian Cancer Survival Socioeconomic status 

Notes

Acknowledgments

The authors would like to thank to all collaborating gynecologists, pathologists, and oncologists who helped to retrieve information for this study and also Mrs Pouran Almstedt, Department of Medical Epidemiology and Biostatistics, for data management, Mrs Margrethe Meo, Cancer Registry of Norway, for secretarial assistance, and Mrs Trudy Perdrix-Thoma for editorial help. No authors have any conflict of interest to declare. This study was funded by grants of the Swedish Cancer Society and Swedish Research Council.

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • Elisabete Weiderpass
    • 1
    • 2
    • 3
    • 4
  • Jin-Kyoung Oh
    • 1
    • 5
  • Sara Algeri
    • 6
  • Rino Bellocco
    • 1
    • 7
  1. 1.Department of Medical Epidemiology and BiostatisticsKarolinska InstitutetStockholmSweden
  2. 2.The Cancer Registry of NorwayOsloNorway
  3. 3.Department of Genetic EpidemiologyFolkhälsan Research CenterHelsinkiFinland
  4. 4.Department of Community MedicineUiT the Arctic University of NorwayTromsöNorway
  5. 5.Risk Appraisal and Prevention Branch, National Cancer Control InstituteNational Cancer CenterGoyangRepublic of Korea
  6. 6.Department of StatisticsTexas A&M UniversityCollege StationUSA
  7. 7.Department of Statistics and Quantitative MethodsUniversity of Milano-BicoccaMilanItaly

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