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Associations of tea and coffee consumption with prostate cancer risk

Cancer Causes & Control volume 24, pages 941–948 (2013)Cite this article

Abstract

Purpose

Tea and coffee contain bioactive compounds and both beverages have recently been associated with a reduced risk of prostate cancer (PCa).

Methods

We studied associations of tea and coffee consumption with PCa risk in a population-based case–control study from King County, Washington, USA. Prostate cancer cases were diagnosed in 2002–2005 and matched to controls by 5-year age groups. Logistic regression was used to generate odds ratios (ORs) and 95 % confidence intervals (CIs).

Results

Among controls, 19 and 58 % consumed at least one cup per day of tea and coffee, respectively. The analysis of tea included 892 cases and 863 controls, and tea consumption was associated with a reduced overall PCa risk with an adjusted OR of 0.63 (95 % CI: 0.45, 0.90; P for trend = 0.02) for men in the highest compared to lowest category of tea intake (≥2 cups/day vs. ≤1 cup/week). Risk estimates did not vary substantially by Gleason grade or disease stage. Coffee consumption was not associated with risk of overall PCa or PCa in subgroups defined by tumor grade or stage.

Conclusions

Our results contribute further evidence that tea consumption may be a modifiable exposure that reduces PCa risk.

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References

  1. Higdon JV, Frei B (2003) Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions. Crit Rev Food Sci Nutr 43:89–143

    Article  PubMed  CAS  Google Scholar 

  2. Yang CS, Wang H, Li GX, Yang Z, Guan F, Jin H (2011) Cancer prevention by tea: evidence from laboratory studies. Pharmacol Res 64:113–122

    Article  PubMed  CAS  Google Scholar 

  3. Arab L (2010) Epidemiologic evidence on coffee and cancer. Nutr Cancer 62:271–283

    Article  PubMed  Google Scholar 

  4. Farah A, Monteiro M, Donangelo CM, Lafay S (2008) Chlorogenic acids from green coffee extract are highly bioavailable in humans. J Nutr 138:2309–2315

    Article  PubMed  CAS  Google Scholar 

  5. Higdon JV, Frei B (2006) Coffee and health: a review of recent human research. Crit Rev Food Sci Nutr 46:101–123

    Article  PubMed  CAS  Google Scholar 

  6. Yang H, Rouse J, Lukes L et al (2004) Caffeine suppresses metastasis in a transgenic mouse model: a prototype molecule for prophylaxis of metastasis. Clin Exp Metastasis 21:719–735

    Article  PubMed  CAS  Google Scholar 

  7. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer J Clin 61:69–90

    Article  PubMed  Google Scholar 

  8. Geybels MS, Verhage BA, Arts IC, van Schooten FJ, Bausch RA, van den Brandt PA (2012) Dietary flavonoid intake, black tea consumption, and risk of overall and advanced stage prostate cancer. Am J Epidemiol. Accepted for publication

  9. Wilson KM, Kasperzyk JL, Rider JR et al (2011) Coffee consumption and prostate cancer risk and progression in the health professionals follow-up study. J Natl Cancer Inst 103:876–884

    Article  PubMed  CAS  Google Scholar 

  10. Park CH, Myung SK, Kim TY, Seo HG, Jeon YJ, Kim Y (2010) Coffee consumption and risk of prostate cancer: a meta-analysis of epidemiological studies. BJU Int 106:762–769

    Article  PubMed  Google Scholar 

  11. Zheng J, Yang B, Huang T, Yu Y, Yang J, Li D (2011) Green tea and black tea consumption and prostate cancer risk: an exploratory meta-analysis of observational studies. Nutr Cancer 63:663–672

    Article  PubMed  CAS  Google Scholar 

  12. Agalliu I, Salinas CA, Hansten PD, Ostrander EA, Stanford JL (2008) Statin use and risk of prostate cancer: results from a population-based epidemiologic study. Am J Epidemiol 168:250–260

    Article  PubMed  Google Scholar 

  13. Patterson RE, Kristal AR, Tinker LF, Carter RA, Bolton MP, Agurs-Collins T (1999) Measurement characteristics of the women’s health initiative food frequency questionnaire. Ann Epidemiol 9:178–187

    Article  PubMed  CAS  Google Scholar 

  14. Yuan JM, Sun C, Butler LM (2011) Tea and cancer prevention: epidemiological studies. Pharmacol Res 64:123–135

    Article  PubMed  CAS  Google Scholar 

  15. Genkinger JM, Li R, Spiegelman D et al (2012) Coffee, tea, and sugar-sweetened carbonated soft drink intake and pancreatic cancer risk: a pooled analysis of 14 cohort studies. Cancer Epidemiol Biomarkers Prev 21:305–318

    Article  PubMed  CAS  Google Scholar 

  16. Jain MG, Hislop GT, Howe GR, Burch JD, Ghadirian P (1998) Alcohol and other beverage use and prostate cancer risk among Canadian men. Int J Cancer 78:707–711

    Article  PubMed  CAS  Google Scholar 

  17. Shafique K, McLoone P, Qureshi K, Leung H, Hart C, Morrison DS (2012) Tea consumption and the risk of overall and grade specific prostate cancer: a large prospective cohort study of Scottish men. Nutr Cancer 64:790–797

    Article  PubMed  CAS  Google Scholar 

  18. Montague JA, Butler LM, Wu AH et al (2012) Green and black tea intake in relation to prostate cancer risk among Singapore Chinese. Cancer Causes Control 23:1635–1641

    Article  PubMed  Google Scholar 

  19. Kyle JA, Morrice PC, McNeill G, Duthie GG (2007) Effects of infusion time and addition of milk on content and absorption of polyphenols from black tea. J Agric Food Chem 55:4889–4894

    Article  PubMed  CAS  Google Scholar 

  20. Henning SM, Wang P, Heber D (2011) Chemopreventive effects of tea in prostate cancer: green tea versus black tea. Mol Nutr Food Res 55:905–920

    Article  PubMed  CAS  Google Scholar 

  21. Shafique K, McLoone P, Qureshi K, Leung H, Hart C, Morrison DS (2012) Coffee consumption and prostate cancer risk: further evidence for inverse relationship. Nutr J 11:42

    Article  PubMed  Google Scholar 

  22. Connors SK, Chornokur G, Kumar NB (2012) New insights into the mechanisms of green tea catechins in the chemoprevention of prostate cancer. Nutr Cancer 64:4–22

    Article  PubMed  CAS  Google Scholar 

  23. Johnson JJ, Bailey HH, Mukhtar H (2010) Green tea polyphenols for prostate cancer chemoprevention: a translational perspective. Phytomedicine 17:3–13

    Article  PubMed  CAS  Google Scholar 

  24. Arts IC, van De Putte B, Hollman PC (2000) Catechin contents of foods commonly consumed in The Netherlands. 2. Tea, wine, fruit juices, and chocolate milk. J Agric Food Chem 48:1752–1757

    Article  PubMed  CAS  Google Scholar 

  25. Arts IC, van de Putte B, Hollman PC (2000) Catechin contents of foods commonly consumed in The Netherlands. 1. Fruits, vegetables, staple foods, and processed foods. J Agric Food Chem 48:1746–1751

    Article  PubMed  CAS  Google Scholar 

  26. Henning SM, Aronson W, Niu Y et al (2006) Tea polyphenols and theaflavins are present in prostate tissue of humans and mice after green and black tea consumption. J Nutr 136:1839–1843

    PubMed  CAS  Google Scholar 

  27. Bettuzzi S, Brausi M, Rizzi F, Castagnetti G, Peracchia G, Corti A (2006) Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: a preliminary report from a one-year proof-of-principle study. Cancer Res 66:1234–1240

    Article  PubMed  CAS  Google Scholar 

  28. Montironi R, Mazzucchelli R, Lopez-Beltran A, Scarpelli M, Cheng L (2011) Prostatic intraepithelial neoplasia: its morphological and molecular diagnosis and clinical significance. BJU Int 108:1394–1401

    Article  PubMed  Google Scholar 

  29. Garcia-Lafuente A, Guillamon E, Villares A, Rostagno MA, Martinez JA (2009) Flavonoids as anti-inflammatory agents: implications in cancer and cardiovascular disease. Inflamm Res 58:537–552

    Article  PubMed  CAS  Google Scholar 

  30. Moon YJ, Wang X, Morris ME (2006) Dietary flavonoids: effects on xenobiotic and carcinogen metabolism. Toxicol In Vitro 20:187–210

    Article  PubMed  CAS  Google Scholar 

  31. Yang CS, Lambert JD, Sang S (2009) Antioxidative and anti-carcinogenic activities of tea polyphenols. Arch Toxicol 83:11–21

    Article  PubMed  CAS  Google Scholar 

  32. Sinha R, Cross AJ, Daniel CR et al (2012) Caffeinated and decaffeinated coffee and tea intakes and risk of colorectal cancer in a large prospective study. Am J Clin Nutr 96:374–381

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

This work was supported by grants from the National Cancer Institute (R01-CA092579) and the Dutch Cancer Society (UM 2009-4556). Additional support was provided by the Fred Hutchinson Cancer Research Center and the Prostate Cancer Foundation. The sponsors of the study had no role in the data analysis, data interpretation, and writing of the report.

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Authors and Affiliations

  1. Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands

    Milan S. Geybels

  2. Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, 1100 Fairview Avenue N, M4‐B874, Seattle, WA, 98109‐1024, USA

    Marian L. Neuhouser & Janet L. Stanford

  3. Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA

    Marian L. Neuhouser & Janet L. Stanford

Authors
  1. Milan S. Geybels
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  2. Marian L. Neuhouser
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  3. Janet L. Stanford
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Corresponding author

Correspondence to Janet L. Stanford.

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Geybels, M.S., Neuhouser, M.L. & Stanford, J.L. Associations of tea and coffee consumption with prostate cancer risk. Cancer Causes Control 24, 941–948 (2013). https://doi.org/10.1007/s10552-013-0170-8

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  • DOI: https://doi.org/10.1007/s10552-013-0170-8

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