The relationship between tumour size and nodal status is more incompatible in triple-negative tumours
I want to congratulate Sopik and Narod for their article  in which they evaluated the relationship between primary tumour size, lymph node status and distant metastases in a cohort of 819,647 women diagnosed with first primary invasive breast cancer. They found that relationship between tumour size, lymph node status and distant metastases in patients with invasive breast cancer is not linear. They found that triple-negative tumours specifically display a smaller increase in lymph node metastasis per 20-mm increase in tumour size than other subtypes for small sizes. Many studies have detected less lymph node metastasis in triple-negative tumours than other subtypes. We studied capillary and lymphatic invasion in tumours of patients with triple-negative tumours. Capillary invasion is more commonly observed than lymphatic invasion in patients with triple-negative tumours . This finding supports the fact that more hematogenous metastasis and less lymph node metastasis were observed in patients with triple-negative tumours.
Author has not received any grants.
Compliance with ethical standards
Conflict of interest
I have no conflict of interest to declare.
My manuscript complies with the Ethical Rules applicable for this journal.
Human and animal rights
This article does not contain any studies with human participants or animals performed by any of the authors.