Breast Cancer Research and Treatment

, Volume 129, Issue 1, pp 281–283 | Cite as

The association between AURKA T91A polymorphism and breast cancer risk

Letter to the Editor


Breast Cancer Allele Frequency Subgroup Analysis Breast Cancer Risk Minor Allele 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Sun H, Bai J, Chen F, Jin Y, Yu Y, Fu S (2011) Lack of an association between AURKA T91A polymorphisms and breast cancer: a meta-analysis involving 32,141 subjects. Breast Cancer Res Treat 125:175–179PubMedCrossRefGoogle Scholar
  2. 2.
    Boccia S, De Feo E, Gallì P, Gianfagna F, Amore R, Ricciardi G (2010) A systematic review evaluating the methodological aspects of meta-analyses of genetic association studies in cancer research. Eur J Epidemiol 25:765–775PubMedCrossRefGoogle Scholar
  3. 3.
    Lewis CM (2002) Genetic association studies: design, analysis and interpretation. Brief Bioinform 3:146–153PubMedCrossRefGoogle Scholar
  4. 4.
    Mantel N, Haenszel W (1959) Statistical aspects of the analysis of data from retrospective studies of disease. J Nat Cancer Inst 22:719–748PubMedGoogle Scholar
  5. 5.
    Tchatchou S, Wirtenberger M, Hemminki K, Sutter C, Meindl A, Wappenschmidt B, Kiechle M, Bugert P, Schmutzler RK, Bartram CR, Burwinkel B (2007) Aurora kinases A and B and familial breast cancer risk. Cancer Lett 247:266–272PubMedCrossRefGoogle Scholar
  6. 6.
    Cox DG, Hankinson SE, Hunter DJ (2006) Polymorphisms of the AURKA (STK15/Aurora Kinase) gene and breast cancer risk (United States). Cancer Causes Control 17:81–83PubMedCrossRefGoogle Scholar
  7. 7.
    Egan KM, Newcomb PA, Ambrosone CB, Trentham-Dietz A, Titus-Ernstoff L, Hampton JM, Kimura MT, Nagase H (2004) STK15 polymorphism and breast cancer risk in a population based study. Carcinogenesis 25:2149–2153PubMedCrossRefGoogle Scholar
  8. 8.
    Fletcher O, Johnson N, Palles C, dos Santos Silva I, McCormack V, Whittaker J, Ashworth A, Peto J (2006) Inconsistent association between the STK15 F31I genetic polymorphism and breast cancer risk. J Natl Cancer Inst 98:1014–1018PubMedCrossRefGoogle Scholar
  9. 9.
    MARIE-GENICA Consortium on Genetic Susceptibility for Menopausal Hormone Therapy Related Breast Cancer Risk (2010) Polymorphisms in the BRCA1 and ABCB1 genes modulate menopausal hormone therapy associated breast cancer risk in postmenopausal women. Breast Cancer Res Treat 120:727–736Google Scholar
  10. 10.
    Vidarsdottir L, Bodvarsdottir SK, Hilmarsdottir H, Tryggvadottir L, Eyfjord JE (2007) Breast cancer risk associated with AURKA 91T→A polymorphism in relation to BRCA mutations. Cancer Lett 250:206–212PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC. 2011

Authors and Affiliations

  1. 1.Department of Clinical LaboratoryTaizhou Municipal HospitalTaizhouChina

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