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Endothelial nitric oxide synthase (eNOS) G894T polymorphism is not associated with breast cancer risk: new evidence

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References

  1. Hao Y, Montiel R, Huang Y (2010) Endothelial nitric oxide synthase (eNOS) 894 G > T polymorphism is associated with breast cancer risk: a meta-analysis. Breast Cancer Res Treat 124(3):809–813

    Article  PubMed  CAS  Google Scholar 

  2. Zintzaras E, Grammatikou M, Kitsios GD, Doxani C, Zdoukopoulos N, Papandreou C, Patrikidou A (2010) Polymorphisms of the endothelial nitric oxide synthase gene in breast cancer: a genetic association study and meta-analysis. J Hum Genet 55(11):743–748

    Article  PubMed  CAS  Google Scholar 

  3. Choi JY, Lee KM, Noh DY, Ahn SH, Lee JE, Han W, Jang IJ, Shin SG, Yoo KY, Hayes RB (2006) Genetic polymorphisms of eNOS, hormone receptor status, and survival of breast cancer. Breast Cancer Res Treat 100(2):213–218

    Article  PubMed  CAS  Google Scholar 

  4. Choi JY, Barlow WE, Albain KS, Hong CC, Blanco JG, Livingston RB, Davis W, Rae JM, Yeh IT, Hutchins LF (2009) Nitric oxide synthase variants and disease-free survival among treated and untreated breast cancer patients in a southwest oncology group clinical trial. Clin Cancer Res 15(16):5258–5266

    Article  PubMed  CAS  Google Scholar 

  5. Ahn J, Ambrosone CB, Kanetsky PA, Tian C, Lehman TA, Kropp S, Helmbold I, von Fournier D, Haase W, Sautter-Bihl ML, Wenz F, Chang-Claude J (2006) Polymorphisms in genes related to oxidative stress (CAT, MnSOD, MPO, and eNOS) and acute toxicities from radiation therapy following lumpectomy for breast cancer. Clin Cancer Res 12(23):7063–7070

    Article  PubMed  CAS  Google Scholar 

  6. Yang J, Ambrosone CB, Hong CC, Ahn J, Rodriguez C, Thun MJ, Calle EE (2007) Relationships between polymorphisms in NOS3 and MPO genes, cigarette smoking and risk of postmenopausal breast cancer. Carcinogenesis 28(6):1247–1253

    Article  PubMed  CAS  Google Scholar 

  7. Hong CC, Ambrosone CB, Ahn J, Choi JY, McCullough ML, Stevens VL, Rodriguez C, Thun MJ, Calle EE (2007) Genetic variability in iron-related oxidative stress pathways (Nrf2, NQ01, NOS3, and HO-1), iron intake, and risk of postmenopausal breast cancer. Cancer Epidemiol Biomarkers Prev 16(9):1784–1794

    Article  PubMed  CAS  Google Scholar 

  8. Li Y, Ambrosone CB, McCullough MJ, Ahn J, Stevens VL, Thun MJ, Hong CC (2009) Oxidative stress-related genotypes, fruit and vegetable consumption and breast cancer risk. Carcinogenesis 30(5):777–784

    Article  PubMed  CAS  Google Scholar 

  9. Lee KM, Choi JY, Lee JE, Noh DY, Ahn SH, Han W, Yoo KY, Hayes RB, Kang D (2007) Genetic polymorphisms of NOS3 are associated with the risk of invasive breast cancer with lymph node involvement. Breast Cancer Res Treat 106(3):433–438

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

This study was supported by Administration of Traditional Chinese Medicine of Zhejiang Province (2007CA113).

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Correspondence to Zhishan Ding.

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Fu, H., Zhang, Y., Jin, L. et al. Endothelial nitric oxide synthase (eNOS) G894T polymorphism is not associated with breast cancer risk: new evidence. Breast Cancer Res Treat 128, 595–598 (2011). https://doi.org/10.1007/s10549-011-1438-x

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  • DOI: https://doi.org/10.1007/s10549-011-1438-x

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