Neoadjuvant chemotherapy for breast cancer: a surgeon’s checklist
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Understanding and translating results from the highly regulated and uniform environment of therapeutic trials to everyday patient care are one of the most challenging aspects of maintaining a clinical breast cancer practice. Careful interpretation of study results is of utmost importance when determining whether or not to adopt a new therapy or treatment sequence. Randomized clinical trials investigating neoadjuvant chemotherapy approaches to breast cancer management deserve special attention from surgeons and all members of the multidisciplinary team to obtain the best result and focus patient goals and expectations.
Each patient for whom neoadjuvant chemotherapy is contemplated should undergo a careful physical exam focused on clinical tumor size, tumor mobility, or fixation with respect to skin and chest wall, axillary lymph node status, and a thorough exam of the contralateral breast. As with any newly diagnosed breast cancer, imaging is intended to characterize the index cancer,...
KeywordsBreast Conservation Postmastectomy Radiotherapy Post Mastectomy Radiotherapy Hormone Responsive Breast Cancer Axillary Nodal Staging
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