Breast Cancer Research and Treatment

, Volume 121, Issue 1, pp 257–260 | Cite as

Broad BRCA1 and BRCA2 mutational spectrum and high incidence of recurrent and novel mutations in the eastern Spain population

  • Eva Esteban Cardeñosa
  • Pascual Bolufer Gilabert
  • Inmaculada de Juan Jimenez
  • Sarai Palanca Suela
  • Eva Barragán González
  • Isabel Chirivella González
  • Ángel Segura Huerta
  • Carmen Guillén Ponce
  • Eduardo Martínez de Dueñas
Letter to the Editor


Genetic Counselling BRCA2 Mutation Deleterious Mutation Frameshift Mutation Pathogenic Mutation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



We express our gratitude to the “Fundación para la Investigación del Hospital Universitario La Fe” for granting two contracts for Inmaculada de Juan and Sarai Palanca (Bch Sc Specialist in Clinical Analysis), which made possible their participation in this study. We also express our gratitude to the support given by the Instituto de Salud Carlos III, grant PI060505, and the Generalitat Valenciana, grants AP-042/07 and EVES 100/2008.


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Copyright information

© Springer Science+Business Media, LLC. 2009

Authors and Affiliations

  • Eva Esteban Cardeñosa
    • 1
  • Pascual Bolufer Gilabert
    • 1
  • Inmaculada de Juan Jimenez
    • 1
  • Sarai Palanca Suela
    • 1
  • Eva Barragán González
    • 1
  • Isabel Chirivella González
    • 2
  • Ángel Segura Huerta
    • 3
  • Carmen Guillén Ponce
    • 4
  • Eduardo Martínez de Dueñas
    • 5
  1. 1.Laboratorio de Biología Molecular, Servicio de Biopatología Clínica, Escuela de Enfermería 7ª PlantaHospital Universitario La FeValenciaSpain
  2. 2.Unit of Genetic Counseling in CancerHospital Clínico UniversitarioValenciaSpain
  3. 3.Unit of Genetic Counseling in CancerHospital Universitario La FeValenciaSpain
  4. 4.Unit of Genetic Counseling in CancerHospital General de ElcheAlicanteSpain
  5. 5.Unit of Genetic Counseling in CancerConsorcio Hospital ProvincialCastellónSpain

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