Does hormonal therapy decrease tamoxifen associated hot flashes?
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The manuscript by Osborne et al.  addresses the question of whether hormonal therapy will decrease hot flashes in patients receiving tamoxifen. Managing hot flushes is important as they are a very challenging side effect of tamoxifen which can negatively impact various areas of a woman’s life; including sleep and relationships.
One of the important aspects of this manuscript regards the role of hot flashes in motivating women to start hormone therapy as well as to stop taking tamoxifen. As an example, in this study the authors report 22 patients who withdrew from the trial related to severe hot flashes. This information leads to a critical point, that being the need to assertively evaluate and manage hot flashes and other related side effects of tamoxifen or any other pharmacologic treatment, whether the purpose of that medication is to prevent or to treat cancer.
Whether hot flash therapies work to different degrees in patients receiving tamoxifen, compared to those who are not...
KeywordsTamoxifen Hormonal Therapy Medroxyprogesterone Acetate Receive Hormone Therapy Progestogen Treatment
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