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Effect of Changes in Stimulus Site on Activation of the Posterior Parietal Cortex

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Abstract

A previous functional magnetic resonance imaging study elucidated the specific activity of the inferior parietal lobe (IPL) during a two-point discrimination task compared with that during an intensity discrimination task Akatsuka et al. (Neuroimage 40: 852-858, 2008). If the posterior parietal cortex (PPC), including IPL, is responsible for detecting changes in stimulus sites, PPC activity depends on the level of change at stimulus sites. The aim of this study was to clarify whether a particular site exists that could detect changes in stimulus sites using the oddball paradigm. Somatosensory-evoked magnetic fields were recorded in 10 right-handed subjects. Three oddball conditions were performed by all subjects, with the probability of deviant and standard stimuli being 20 and 80 %, respectively, under all three conditions. Deviant stimuli were always presented to the second digit of the hand and standard stimuli were presented to the first (small deviance: SD) and fifth digits (medium deviance: MD) of the hand and the first digit of the toe (large deviance: LD). Inter-stimulus intervals were set at 500 ms. A brain electrical source analysis showed that activities of areas 1 and 3b elicited by the deviant stimuli were not significantly different among the three conditions. In contrast, PPC activity was significantly greater for LD than for SD and MD. PPC activity tended to increase with greater deviance at stimulus sites, but activities of areas 1 and 3b did not differ. These findings suggest that PPC may have a functional role in automatic change detection systems with regard to deviance of stimulus sites.

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Acknowledgments

This study was supported by a Grant-in-aid for young scientists (B) from the Japan Society for the Promotion of Science (JSPS) and a Grant-in-aid for Advanced Research from Niigata University of Health and Welfare.

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Authors and Affiliations

  1. Institute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata, 950-3198, Japan

    Koya Yamashiro, Daisuke Sato, Hideaki Onishi, Kazuhiro Sugawara, Sho Nakazawa & Atsuo Maruyama

  2. Department of Neurosurgery, Nishi-Niigata Chuo National Hospital, Niigata, Japan

    Shigeki Kameyama

Authors
  1. Koya Yamashiro
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  2. Daisuke Sato
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  3. Hideaki Onishi
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  4. Kazuhiro Sugawara
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  5. Sho Nakazawa
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  6. Shigeki Kameyama
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  7. Atsuo Maruyama
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Correspondence to Koya Yamashiro.

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Yamashiro, K., Sato, D., Onishi, H. et al. Effect of Changes in Stimulus Site on Activation of the Posterior Parietal Cortex. Brain Topogr 28, 261–268 (2015). https://doi.org/10.1007/s10548-014-0378-2

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  • DOI: https://doi.org/10.1007/s10548-014-0378-2

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