Bioscience Reports

, Volume 24, Issue 4–5, pp 302–322 | Cite as

Drugs from Emasculated Hormones: The Principle of Syntopic Antagonism

  • James Black
Nobel Lecture


This lecture outlines the early stages in the discovery of adrenaline β-receptor antagonists and of the histamine H2-receptor antagonists. It ends with a brief personal view about future research.

Key words:

β-adrenergic receptor histamine receptor hormone antagonism 


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Copyright information

© Springer Science+Business Media, Inc. 2005

Authors and Affiliations

  • James Black
    • 1
  1. 1.Department of Analytical Pharmacology Rayne InstituteKing’s College School of Medicine & DentistryLondonUK

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