Biologia Plantarum

, Volume 62, Issue 4, pp 617–629 | Cite as

The role of plant cation/proton antiporter gene family in salt tolerance

  • Q. Jia
  • C. Zheng
  • S. Sun
  • H. Amjad
  • K. Liang
  • W. Lin


Salinity is one of the major abiotic constraints to agriculture. The physiological and molecular mechanisms of salt tolerance have been studied in plants for many years. The regulation of osmosis and ion homeostasis is crucial. A lot of important components involved in plant responses to salt stress have been identified. Among them, ion transporters and channels take an essential role in ion homeostasis, mainly for Na+, Cl-, and K+. Until now, many cation antiporters important for salt tolerance in plants have been characterized. Among them, the monovalent cation/proton antiporters (CPA) family is one of the most important families, including sodium proton exchangers (NHXs), K+-efflux antiporters (KEAs), and cation/H+ exchangers (CHXs). Here, the current knowledge of the plant CPA family in responses to salt stress is reviewed. The regulation mechanisms were also included and discussed.

Additional key words

Na+/H+ exchanger K+-efflux antiporter cation/H+ exchanger 



abscisic acid-insensitive 2


calmodulin-like protein 15


calcineurin B-like


coding sequence


cation/H+ exchanger


CBL-interacting serine/threonine-protein kinase 24


cation/proton antiporter


ethylene-insensitive 3


endoplasmic reticulum


ethylene and salt-inducible ERF1






high-affinity K+ transporter 5


high-affinity K+ transporter


K+-efflux antiporter


K+ uptake transporter


sodium potassium root defective 3


sodium proton exchanger


non selective channels


plasma membrane


plasma membrane H+-ATPase


plasma membrane H+-PPase


pre-vacuolar compartments


reactive oxygen species


SOS3-like calcium binding protein 8


salt overly sensitive


transcription factor


trans-Golgi network


universal stress protein


untranslated region


tonoplast H+-ATPase


tonoplast H+-PPase


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Supplementary material

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Copyright information

© The Institute of Experimental Botany 2018

Authors and Affiliations

  • Q. Jia
    • 1
    • 2
  • C. Zheng
    • 1
  • S. Sun
    • 1
  • H. Amjad
    • 2
  • K. Liang
    • 1
  • W. Lin
    • 1
    • 2
  1. 1.Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, College of Crop ScienceFujian Agriculture and Forestry UniversityFuzhouP.R. China
  2. 2.Key Laboratory of Crop Ecology and Molecular PhysiologyFujian Province UniversityFuzhouP.R. China

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