Biologia Plantarum

, Volume 58, Issue 3, pp 401–410 | Cite as

The B subfamily of plant ATP binding cassette transporters and their roles in auxin transport



The ATP binding cassette B/multidrug-resistance/P-glycoprotein (ABCB/MDR/PGP) subfamily is a member of the ABC protein family. Significant progress has been made in the functional characterization of ABCB genes, particularly in Arabidopsis thaliana. This review evaluates recent advances concerning the plant ABCB subfamilies including their evolution and structure, the involvement and regulation of ABCB-mediated auxin transport, and the roles of ABCBs in plant growth and development. Insights into specific functions of members of the ABCB subfamily and their mediation of various regulatory pathways are also presented.

Additional key words

ABC protein family gene expression phylogenetic tree subcellular localization transgenic plants 



ATP binding cassette


ATP binding cassette B






nucleotide-binding domains


1-naphthylphthalamic acid










transmembrane domains


immunophilin-like FKBP42 TWISTED DWARF1


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Supplementary material

10535_2014_423_MOESM1_ESM.pdf (78 kb)
Supplementary material, approximately 78 KB.


  1. Abel, S., Theologis, A.: The odyssey of auxin. — Cold Spring Harbour Perspect Biol. 2: a004572, 2010.Google Scholar
  2. Ambudkar, S., Dey, S., Hrycyna, C., Ramachandra, M., Pastan, I., Gottesman, M.: Biochemical, cellular, and pharmacological aspects of the multidrug transporter. — Annu. Rev. Pharmacol. Toxicol. 39: 361–398, 1999.PubMedCrossRefGoogle Scholar
  3. Bailly, A., Sovero, V., Vincenzetti, V., Santelia, D., Bartnik, D., Koenig, B.W., Mancuso, S., Martinoia, E., Geisler, M.: Modulation of P-glycoproteins by auxin transport inhibitors is mediated by interaction with immunophilins. — J. biol. Chem. 28: 21817–21826, 2008.CrossRefGoogle Scholar
  4. Baluska, F., Samaj, J., Menzel, D.: Polar transport of auxin: carrier-mediated flux across the plasma membrane or neurotransmitter-like secretion? — Trends Cell Biol. 13: 282–285, 2003.PubMedCrossRefGoogle Scholar
  5. Bandyopadhyay, A., Blakeslee, J.J., Lee, O.R., Mravec, J., Sauer, M., Titapiwatanakun, B., Makam, S.N., Bouchard, R., Geisler, M., Martinoia, E., Friml, J., Peer, W.A., Murphy, A.S.: Interactions of PIN and PGP auxin transport mechanisms. — Biochem. Soc. Trans. 35: 137–141, 2007.PubMedCrossRefGoogle Scholar
  6. Blakeslee, J.J., Bandyopadhyay, A., Lee, O.R., Mravec, J., Titapiwatanakun, B., Sauer, M., Makam, S.N., Cheng, Y., Bouchard, R., Adamec, J., Geisler, M., Nagashima, A., Sakai, T., Martinoia, E., Friml, J., Peer, W.A., Murphy, A.S.: Interactions among PINFORMED and P-glycoprotein auxin transporters in Arabidopsis thaliana. — Plant Cell 19: 131–147, 2007.PubMedCentralPubMedCrossRefGoogle Scholar
  7. Blakeslee, J.J., Peer, W.A., Murphy, A.S.: MDR/PGP auxin transport proteins and endocytic cycling. — In: In: Samaj, J., Baluska, F., Menze, D. (ed.): Plant Endocytosis. Pp. 159–176. Springer-Verlag, Berlin — Heidelberg 2005.CrossRefGoogle Scholar
  8. Bouchard, R., Bailly, A., Blakeslee, J.J., Oehring, S.C., Vincenzetti, V., Lee, O.R., Paponov, I., Palme, K., Mancuso, S., Murphy, A.S., Schulz, B., Geisler, M.: Immunophilin-like TWISTED DWARF1 modulates auxin efflux activities of Arabidopsis P-glycoproteins. — J. biol. Chem. 281: 30603–30612, 2006.PubMedCrossRefGoogle Scholar
  9. Brown, D.E., Rashotte, A.M., Murphy, A.S., Normanly, J., Tague, B.W., Peer, W.A., Taiz, L., Muday, G.K.: Flavonoids act as negative regulators of auxin transport in vivo in Arabidopsis. — Plant Physiol. 126: 524–535, 2001.PubMedCentralPubMedCrossRefGoogle Scholar
  10. Cho, M., Lee, S.H., Cho, H.T.: P-glycoprotein4 displays auxin efflux transporter-like action in Arabidopsis root hair cells and tobacco cells. — Plant Cell 19: 3930–3943, 2007.PubMedCentralPubMedCrossRefGoogle Scholar
  11. Christie, J.M., Yang, H., Richter, G.L., Sullivan, S., Thomson, C.E., Lin, J., Titapiwatanakun, B., Ennis, M., Kaiserli, E., Lee, O.R., Adamec, J., Peer, W.A., Murphy, A.S.: phot1 inhibition of ABCB19 primes lateral auxin fluxes in the shoot apex required for phototropism. — PLoS Biol. 9: e1001076, 2011.PubMedCentralPubMedCrossRefGoogle Scholar
  12. Crouzet, J., Roland, J., Peeters, E., Trombik, T., Ducos, E., Nader, J., Boutry, M.: NtPDR1, a plasma membrane ABC transporter from Nicotiana tabacum, is involved in diterpene transport. — Plant mol. Biol. 82: 181–192, 2013.PubMedCrossRefGoogle Scholar
  13. Davies, T.G.E., Theodoulou, F.L., Hallahan, D.L., Forde, B.G.: Cloning and characterisation of a novel p-glycoprotein homologue from barley. — Gene 199: 195–202, 1997.PubMedCrossRefGoogle Scholar
  14. Ferte, J., Kuhnel, J.M., Chapuis, G., Rolland, Y., Lewin, G., Schwaller, M.A.: Flavonoid-related modulators of multidrug resistance: synthesis, pharmacological activity, and structureactivity relationships. — J. med. Chem. 42: 478–489, 1999.PubMedCrossRefGoogle Scholar
  15. Geisler, M., Blakeslee, J.J., Bouchard, R., Lee, O.R., Vincenzetti, V., Bandyopadhyay, A., Titapiwatanakun, B., Peer, W.A., Bailly, A., Richards, E.L., Ejendal, K.F., Smith, A.P., Baroux, C., Grossniklaus, U., Müller, A., Hrycyna, C.A., Dudler, R., Murphy, A.S., Martinoia, E.: Cellular efflux of auxin catalyzed by the Arabidopsis MDR/PGP transporter AtPGP1. — Plant J. 44: 179–194, 2005.PubMedCrossRefGoogle Scholar
  16. Geisler, M., Girin, M., Brandt, S., Vincenzetti, V., Plaza, S., Paris, N., Kobae, Y., Maeshima, M., Billion, K., Kolukisaoglu, U.H., Schulz, B., Martinoia, E.: Arabidopsis immunophilin-like TWD1 functionally interacts with vacuolar ABC transporters. — Mol. Biol. Cell 15: 3393–3405, 2004.PubMedCentralPubMedCrossRefGoogle Scholar
  17. Geisler, M., Kolukisaoglu, H.U., Bouchard, R., Billion, K., Berger, J., Saal, B., Frangne, N., Koncz-Kalman, Z., Koncz, C., Dudler, R., Blakeslee, J.J., Murphy, A.S., Martinoia, E., Schulz, B.: TWISTED DWARF1, a unique plasma membrane-anchored immunophilin-like protein, interacts with Arabidopsis multidrug resistance-like transporters AtPGP1 and AtPGP19. — Mol. Biol. Cell 14: 4238–4249, 2003.PubMedCentralPubMedCrossRefGoogle Scholar
  18. Goto, N., Starke, M., Kranr, A.R.: Effect of gibberellins on flower development of the pin-formed mutant of Arabidopsis thaliana. — Arabidopsis Inf. Serv. 23: 66–71, 1987.Google Scholar
  19. Henrichs, S., Wang, B., Fukao, Y., Zhu, J., Charrier, L., Bailly, A., Oehring, S.C., Linnert, M., Weiwad, M., Endler, A., Nanni, P., Pollmann, S., Mancuso, S., Schulz, A., Geisler, M.: Regulation of ABCB1/PGP1-catalysed auxin transport by linker phosphorylation. — EMBO J. 31: 2965–2980, 2012.PubMedCentralPubMedCrossRefGoogle Scholar
  20. Jasinski, M., Ducos, E., Martinoia, E., Boutry, M.: The ATPbinding cassette transporters: structure, function, and gene family comparison between rice and Arabidopsis. — Plant Physiol. 131: 1169–1177, 2003.PubMedCentralPubMedCrossRefGoogle Scholar
  21. Kamimoto, Y., Terasaka, K., Hamamoto, M., Takanashi, K., Fukuda, S., Shitan, N., Sugiyama, A., Suzuki, H., Shibata, D., Wang, B., Pollmann, S., Geisler, M., Yazaki, K.: Arabidopsis ABCB21 is a facultative auxin importer/ exporter regulated by cytoplasmic auxin concentration. — Plant Cell Physiol. 53: 2090–2100, 2012.PubMedGoogle Scholar
  22. Klein, M., Geisler, M., Suh, S.J., Kolukisaoglu, H.U., Azevedo, L., Plaza, S., Curtis, M.D., Richter, A., Weder, B., Schulz, B., Martinoia, E.: Disruption of AtMRP4, a guard cell plasma membrane ABCC-type ABC transporter, leads to deregulation of stomatal opening and increased drought susceptibility. — Plant J. 39: 219–236, 2004.PubMedCrossRefGoogle Scholar
  23. Knöller, A.S., Blakeslee, J.J., Richards, E.L., Peer, W.A., Murphy, A.S.: Brachytic2/ZmABCB1 functions in IAA export from intercalary meristems. — J. exp. Bot. 61: 3689–3696, 2010.PubMedCentralPubMedCrossRefGoogle Scholar
  24. Krouk, G., Lacombe, B., Bielach, A., Perrine-Walker, F., Malinska, K., Mounier, E., Hoyerova, K., Tillard, P., Leon, S., Ljung, K., Zazimalova, E., Benkova, E., Nacry, P., Gojon, A.: Nitrate-regulated auxin transport by NRT1.1 defines a mechanism for nutrient sensing in plants. — Dev. Cell 18: 927–937, 2010.PubMedCrossRefGoogle Scholar
  25. Kubeš, M., Yang, H., Richter, G.L., Cheng, Y., Młodzińska, E., Wang, X., Blakeslee, J.J., Carraro, N., Petrášek, J., Zažímalová, E., Hoyerová, K., Peer, W.A., Murphy, A.S.: The Arabidopsis concentration-dependent influx/efflux transporter ABCB4 regulates cellular auxin levels in the root epidermis. — Plant J. 69: 640–654, 2012.PubMedCrossRefGoogle Scholar
  26. Lee, M., Choi, Y., Burla, B., Kim, Y.Y., Jeon, B., Maeshima, M., Yoo, J.Y., Martinoia, E., Lee, Y.: The ABC transporter AtABCB14 is a malate importer and modulates stomatal response to CO2. — Nat. Cell Biol. 10: 1217–1223, 2008.PubMedCrossRefGoogle Scholar
  27. Lee, M., Lee, K., Lee, J., Noh, E.W., Lee, Y.: AtPDR12 contributes to lead resistance in Arabidopsis. — Plant Physiol. 138: 827–836, 2005.PubMedCentralPubMedCrossRefGoogle Scholar
  28. Le Hir, R., Sorin, C., Chakraborti, D., Moritz, T., Schaller, H., Tellier, F., Robert, S., Morin, H., Bako, L., Bellini, C.: ABCG9, ABCG11 and ABCG14 ABC transporters are required for vascular development in Arabidopsis. — Plant J. 76: 811–824, 2013.PubMedCrossRefGoogle Scholar
  29. Lewis, D.R., Miller, N.D., Splitt, B.L., Wu, G., Spalding, E.P.: Separating the roles of acropetal and basipetal auxin transport on gravitropism with mutations in two Arabidopsis multidrug resistance-like ABC transporter genes. — Plant Cell 19: 1838–1850, 2007.PubMedCentralPubMedCrossRefGoogle Scholar
  30. Lewis, D.R., Wu, G., Ljung, K., Spalding, E.P.: Auxin transport into cotyledons and cotyledon growth depend similarly on the ABCB19 multidrug resistance-like transporter. — Plant J. 60: 91–101, 2009.PubMedCrossRefGoogle Scholar
  31. Lin, R., Wang, H.: Two homologous ATP-binding cassette transporter proteins, AtMDR1 and AtPGP1, regulate Arabidopsis photomorphogenesis and root development by mediating polar auxin transport. — Plant Physiol. 138: 949–964, 2005.PubMedCentralPubMedCrossRefGoogle Scholar
  32. Liu, Q., Zhou, G.Q., Xu, F., Yan, X.L., Liao, H., Wang, J.X.: The involvement of auxin in root architecture plasticity in Arabidopsis induced by heterogeneous phosphorus availability. — Biol. Plant. 57: 739–748, 2013.CrossRefGoogle Scholar
  33. Ljung, K., Hull, A.K., Celenza, J., Yamada, M., Estelle, M., Normanly, J., Sandberg, G.: Sites and regulation of auxin biosynthesis in Arabidopsis roots. — Plant Cell 17: 1090–1104, 2005.PubMedCentralPubMedCrossRefGoogle Scholar
  34. Martinoia, E., Klein, M., Geisler, M., Bovet, L., Forestier, C., Kolukisaoglu, U., Müller-Röber, B., Schulz, B.: Multifunctionality of plant ABC transporters-more than just detoxifiers. — Planta 214: 345–355, 2002.PubMedCrossRefGoogle Scholar
  35. Mravec, J., Kubes, M., Bielach, A., Gaykova, V., Petrásek, J., Skůpa, P., Chand, S., Benková, E., Zazímalová, E., Friml, J.: Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development. — Development 135: 3345–3354, 2008.PubMedCrossRefGoogle Scholar
  36. Multani, D.S., Briggs, S.P., Chamberlin, M.A., Blakeslee, J.J., Murphy, A.S., Johal, G.S.: Loss of an MDR transporter in compact stalks of maize br2 and sorghum dw3 mutants. — Science 302: 81–84, 2003.PubMedCrossRefGoogle Scholar
  37. Murphy, A., Peer, W., Blakeslee, J.J., Lee, O.R., Bandyopadhyay, A., Titapiwatanakun, B., Richards, E., Smith, A., Geisler, M., Martinoia, E., Ejendal, K.F.K., Hrycyna, C.A.: Transport. — Biol. Plant. 49 (Suppl): S9, 2005.Google Scholar
  38. Murphy, A.S., Hoogner, K.R., Peer, W.A., Taiz, L.: Identification, purification, and molecular cloning of N-1-naphthylphthalmic acid-binding plasma membrane-associated aminopeptidases from Arabidopsis. — Plant Physiol. 128: 935–950, 2002.PubMedCentralPubMedCrossRefGoogle Scholar
  39. Murphy, A.S., Peer, W.A., Taiz, L.: Regulation of auxin transport by aminopeptidases and endogenous flavonoids. — Planta 211: 315–324, 2000.PubMedCrossRefGoogle Scholar
  40. Noh, B., Bandyopadhyay, A., Peer, W.A., Spalding, E.P., Murphy, A.S. Enhanced gravi- and phototropism in plant mdr mutants mislocalizing the auxin efflux protein PIN1. — Nature 423: 999–1002, 2003.PubMedCrossRefGoogle Scholar
  41. Noh, B., Murphy, A.S., Spalding, E.P.: Multidrug resistance-like genes of Arabidopsis required for auxin transport and auxinmediated development. — Plant Cell 13: 2441–2454, 2001.PubMedCentralPubMedCrossRefGoogle Scholar
  42. Nuhse, T.S., Stensballe, A., Jensen, O.N., Peck, S.C.: Phosphoproteomics of the Arabidopsis plasma membrane and a new phosphorylation site database. — Plant Cell 16: 2394–2405, 2004.PubMedCentralPubMedCrossRefGoogle Scholar
  43. Okada, K., Shimura, Y.: Modulation of Root Growth by Physical Stimuli in Arabidopsis. — Cold Spring Harbor Laboratory Press, Cold Spring Harbor 1994.Google Scholar
  44. Okada, K., Ueda, J., Komaki, M.K., Bell, C.J., Shimura, Y.: Requirement of the auxin polar transport-system in early stages of Arabidopsis floral bud formation. — Plant Cell 3: 677–684, 1991.PubMedCentralPubMedCrossRefGoogle Scholar
  45. Park, B.S., Sang, W.G., Song, J.T., Lee, B.H., Kim, J.H., Se, H.S.: Auxin is involved in the regulation of leaf and root development by LAF1 under short day conditions. — Biol. Plant. 55: 647–652, 2011.CrossRefGoogle Scholar
  46. Peer, W.A., Bandyopadhyay, A., Blakeslee, J.J., Makam, S.N., Chen, R.J., Mason, P.H., Murphy, A.S.: Variation in expression and protein localization of the PIN family of auxin efflux facilitator proteins in flavonoid mutants with altered auxin transport in Arabidopsis thaliana. — Plant Cell 16: 1898–1911, 2004.PubMedCentralPubMedCrossRefGoogle Scholar
  47. Peer, W.A., Blakeslee, J.J., Yang, H., Murphy, A.S.: Seven things we think we know about auxin transport. — Mol. Plant 4: 487–504, 2011.PubMedCrossRefGoogle Scholar
  48. Peer, W.A., Brown, D.E., Tague, B.W., Muday, G.K., Taiz, L., Murphy, A.S.: Flavonoid accumulation patterns of transparent testa mutants of Arabidopsis. — Plant Physiol. 126: 536–548, 2001.PubMedCentralPubMedCrossRefGoogle Scholar
  49. Petrášek, J., Friml, J.: Auxin transport routes in plant development. — Development 136: 2675–2688, 2009.PubMedCrossRefGoogle Scholar
  50. Petrásek, J., Mravec, J., Bouchard, R., Blakeslee, J.J., Abas, M., Seifertová, D., Wisniewska, J., Tadele, Z., Kubes, M., Covanová, M., Dhonukshe, P., Skupa, P., Benková, E., Perry, L., Krecek, P., Lee, O.R., Fink, G.R., Geisler, M., Murphy, A.S., Luschnig, C., Zazímalová, E., Friml, J.: PIN proteins perform a rate-limiting function in cellular auxin efflux. — Science 312: 914–918, 2006.PubMedCrossRefGoogle Scholar
  51. Sandberg, G., Tarkowski, P., Petersson, S.V., Tarkowska, D., Benfey, P., Dolezal, K., Ljung, K.: Auxin-cytokinin crosstalk and interaction with other hormones. — Biol. Plant. 49(Suppl): S26, 2005.Google Scholar
  52. Rea, P.A.: Plant ATP-binding cassette transporters. — Annu. Rev. Plant Biol. 58: 347–375, 2007.PubMedCrossRefGoogle Scholar
  53. Richter, S., Geldner, N., Schrader, J., Wolters, H., Stierhof, Y.D., Rios, G., Koncz, C., Robinson, D.G., Jurgens, G.: Functional diversification of closely related ARF-GEFs in protein secretion and recycling. — Nature 448: 488–492, 2007.PubMedCrossRefGoogle Scholar
  54. Rojas-Pierce, M., Titapiwatanakun, B., Sohn, E.J., Fang, F., Larive, C.K., Blakeslee, J., Cheng, Y., Cutler, S.R., Peer, W.A., Murphy, A.S., Raikhel, N.V.: Arabidopsis P-glycoprotein19 participates in the inhibition of gravitropism by gravacin. — Chem. Biol. 14: 1366–1376, 2007.PubMedCrossRefGoogle Scholar
  55. Santelia, D., Vincenzetti, V., Azzarello, E., Bovet, L., Fukao, Y., Düchtig, P., Mancuso, S., Martinoia, E., Geisler, M.: MDRlike ABC transporter AtPGP4 is involved in auxin-mediated lateral root and root hair development. — FEBS Lett. 579: 5399–5406, 2005.PubMedCrossRefGoogle Scholar
  56. Sasaki, T., Ezaki, B., Matsumoto, H.: A gene encoding multidrug resistance (MDR) -like protein is induced by aluminum and inhibitors of calcium flux in wheat. — Plant Cell Physiol. 43: 177–185, 2002.PubMedGoogle Scholar
  57. Schiefelbein, J.W.: Constructing a plant cell. The genetic control of root hair development. — Plant Physiol. 124: 1525–1531, 2000.PubMedCentralPubMedCrossRefGoogle Scholar
  58. Shen, C., Bai, Y., Wang, S., Zhang, S., Wu, Y., Chen, M., Jiang, D., Qi, Y.: Expression profile of PIN, AUX/LAX and PGP auxin transporter gene families in Sorghum bicolor under phytohormone and abiotic stress. — FEBS J. 277: 2954–2969, 2010.PubMedCrossRefGoogle Scholar
  59. Shitan, N., Bazin, I., Dan, K., Obata, K., Kigawa, K., Ueda, K., Sato, F., Forestier, C., Yazaki, K.: Involvement of CjMDR1, a plant multidrug-resistance-type ATP-binding cassette protein, in alkaloid transport in Coptis japonica. — Proc. nat. Acad. Sci. USA 100: 751–756, 2003.PubMedCentralPubMedCrossRefGoogle Scholar
  60. Shitan, N., Dalmas, F., Dan, K., Kato, N., Ueda, K., Sato, F., Forestier, C., Yazaki, K.: Characterization of Coptis japonica CjABCB2, an ATP-binding cassette protein involved in alkaloid transport. — Phytochemistry 9: 109–116, 2013.CrossRefGoogle Scholar
  61. Sidler, M., Hassa, P., Hasan, S., Ringli, C., Dudler, R.: Involvement of an ABC transporter in a developmental pathway regulating hypocotyl cell elongation in the light. — Plant Cell 10: 1623–1636, 1998.PubMedCentralPubMedCrossRefGoogle Scholar
  62. Swarup, R., Bennett, M.: Auxin transport: the fountain of life in plants? — Dev. Cell 5: 824–826, 2003.PubMedCrossRefGoogle Scholar
  63. Takanashi, K., Sugiyama, A., Sato, S., Tabata, S., Yazaki.: LjABCB1, an ATP-binding cassette protein specifically induced in uninfected cells of Lotus japonicus nodules. — J. Plant Physiol. 169: 322–326, 2012.PubMedCrossRefGoogle Scholar
  64. Takanashi, K., Sugiyama, A., Yazaki, K.: Involvement of auxin distribution in root nodule development of Lotus japonicus. — Planta 234:73–81, 2011.PubMedCrossRefGoogle Scholar
  65. Tanaka, H., Dhonukshe, P., Brewer, P.B., Friml, J.: Spatiotemporal asymmetric auxin distribution: a mean to coordinate plant development. — Cell Mol. Life Sci. 63: 2738–2754, 2006.PubMedCrossRefGoogle Scholar
  66. Teale, W.D., Paponov, I., Palme, K.: Auxin in action: signalling, transport and the control of plant growth and development. — Nat. Rev. mol. cell. Biol. 7: 847–859, 2006.PubMedCrossRefGoogle Scholar
  67. Terasaka, K., Blakeslee, J.J., Titapiwatanakun, B., Peer, W.A., Bandyopadhyay, A., Makam, S.N., Lee, O.R., Richards, E.L., Murphy, A.S., Sato, F., Yazaki, K.: PGP4, an ATP binding cassette P glycoprotein, catalyzes auxin transport in Arabidopsis thaliana roots. — Plant Cell 17: 2922–2939, 2005.PubMedCentralPubMedCrossRefGoogle Scholar
  68. The, O.K., Moore, I.: An ARF-GEF acting at the Golgi and in selective endocytosis in polarized plant cells. — Nature 448: 493–496, 2007.CrossRefGoogle Scholar
  69. Titapiwatanakun, B., Blakeslee, J.J., Bandyopadhyay, A., Yang, H., Mravec, J., Sauer, M., Cheng, Y., Adamec, J., Nagashima, A., Geisler, M., Sakai, T., Friml, J., Peer, W.A., Murphy, A.S.: ABCB19/PGP19 stabilizes PIN1 on membrane microdomains in Arabidopsis. — Plant J. 57: 27–44, 2008.PubMedCrossRefGoogle Scholar
  70. Titapiwatanakun, B., Murphy, A.S.: Post-transcriptional regulation of auxin transport proteins: cellular trafficking, protein phosphorylation, protein maturation, ubiquitination, and membrane composition. — J. exp. Bot. 60: 1093–1107, 2008.PubMedCrossRefGoogle Scholar
  71. Verrier, P.J., Bird, D., Burla, B., Dassa, E., Forestier, C., Geisler, M., Klein, M., Kolukisaoglu, U., Lee, Y., Martinoia, E., Murphy, A., Rea, P.A., Samuels, L., Schulz, B., Spalding, E.J., Yazaki, K., Theodoulou, F.L.: Plant ABC proteins — a unified nomenclature and updated inventory. — Trends Plant Sci. 13: 151–159, 2008.PubMedCrossRefGoogle Scholar
  72. Vieten, A., Sauer, M., Brewer, P.B., Friml, J.: Molecular and cellular aspects of auxin-transport-mediated development. — Trends Plant Sci. 12: 160–168, 2007.PubMedCrossRefGoogle Scholar
  73. Wang, B., Bailly, A., Zwiewka, M., Henrichs, S., Azzarello, E., Mancuso, S., Maeshima, M., Friml, J., Schulz, A., Geisler, M.: Arabidopsis TWISTED DWARF1 functionally interacts with auxin exporter ABCB1 on the root plasma membrane. — Plant Cell 25: 202–214, 2013.PubMedCentralPubMedCrossRefGoogle Scholar
  74. Wang, W., Takezawa, D., Poovaiah, B.W.: A potato cDNA encoding a homologue of mammalian multidrug resistant Pglycoprotein. — Plant mol. Biol. 31: 683–687, 1996.PubMedCrossRefGoogle Scholar
  75. Wisniewska, J., Xu, J., Seifertová, D., Brewer, P.B., Ruzicka, K., Blilou, I., Rouquié, D., Benková, E., Scheres, B., Friml, J.: Polar PIN localization directs auxin flow in plants. — Science 312: 883, 2006.PubMedCrossRefGoogle Scholar
  76. Wu, G., Lewis, D.R., Spalding, E.P.: Mutations in Arabidopsis multidrug resistance-like ABC transporters separate the roles of acropetal and basipetal auxin transport in lateral root development. — Plant Cell 19: 1826–1837, 2007.PubMedCentralPubMedCrossRefGoogle Scholar
  77. Wu, G., Otegui, M.S., Spalding, E.P.: The ER-localized TWD1 immunophilin is necessary for localization of multidrug resistance-like proteins required for polar auxin transport in Arabidopsis roots. — Plant Cell 22: 3295–3304, 2010.PubMedCentralPubMedCrossRefGoogle Scholar
  78. Yang, H., Murphy, A.S.: Functional expression and characterization of Arabidopsis ABCB, AUX 1 and PIN auxin transporters in Schizosaccharomyces pombe. — Plant J. 59: 179–191, 2009.PubMedCrossRefGoogle Scholar
  79. Zazímalová, E., Murphy, A.S., Yang, H., Hoyerová, K., Hosek, P.: Auxin transporters — why so many? — Cold Spring Harbour Perspect Biol. 2: a001552, 2010.Google Scholar
  80. Zhang, L., Lu, X., Shen, Q., Chen, Y.F., Wang, T., Zhang, F.Y., Wu, S.Y., Jiang, W.M., Liu, P., Zhang, L.D., Wang, Y.Y., Tang, K.X.: Identification of putative artemisia annua ABCG transporter unigenes related to artemisinin yield following expression analysis in different plant tissues and in response to methyl jasmonate and abscisic acid treatments. — Plant mol. Biol. Rep. 30: 838–847, 2012.CrossRefGoogle Scholar

Copyright information

© The Institute of Experimental Botany 2014

Authors and Affiliations

  1. 1.State Key Laboratory of Plant Physiology and Biochemistry, College of Life SciencesZhejiang UniversityHangzhouP.R. China
  2. 2.Tianmu CollegeZhejiang A & F UniversityZhujiP.R. China

Personalised recommendations