Table 3 Antihyaluronidase activity of the extracts obtained from the mycelial cultures of Ganoderma applanatum, Laetiporus sulphureus, and Trametes versicolor

From: Mycelial culture extracts of selected wood-decay mushrooms as a source of skin-protecting factors

Concentration [µg/mL] Inhibition of hyaluronidase activity (%)
Ganoderma applanatum Laetiporus sulphureus Trametes versicolor Positive control
3000 1.56 ± 1.02*** 97.76 ± 1,27 ns 24.28 ± 0.63*** 96.57 ± 1.33
2000 0.67 ± 0.67*** 93.50 ± 0.36 ns 16.67 ± 0.49*** 95.27 ± 1.39
1000 0.23 ± 0.39*** 87.76 ± 6.49 ns 6.99 ± 0.70*** 91.11 ± 1.50
700 0.00 ± 0.00*** 34.18 ± 2.90*** 2.86 ± 0.45*** 80.56 ± 0.75
500 0.00 ± 0.00*** 6.22 ± 0.77*** 2.17 ± 1.92*** 38.84 ± 1.33
300 0.00 ± 0.00*** 2.55 ± 1.10*** 0.00 ± 0.00*** 21.86 ± 4.04
200 0.00 ± 0.00*** 0.43 ± 0.75*** 0.00 ± 0.00*** 13.86 ± 2.70
100 0.00 ± 0.00* 0.00 ± 0.00* 0.00 ± 0.00* 4.39 ± 0.88
0 0.00 ± 0.00 ns 0.00 ± 0.00 ns 0.00 ± 0.00 ns 0.00 ± 0.00
IC50 [µg/mL]  > 3000 760.01  > 3000 509.79
  1. Positive control: quercetin (dihydrate)
  2. Data are presented as the mean ± SD (standard deviation); n = 3 repetitions. Anova test was used to reveal the differences between paired groups of elements in rows
  3. *Differences statistically significant for p < 0.05 vs. positive control
  4. **Differences statistically significant for p < 0.01 vs. positive control
  5. ***Differences statistically significant for p < 0.001 vs. positive control
  6. ns not statistically significant
  7. (Statsoft STATISTICA)