Investigation of Hemocompatibility of Rotary Blood Pumps: The Case of the Sputnik Ventricular Assist Device

The hemocompatibility of Sputnik rotary blood pumps of the first and second generation (Sputnik-1 and Sputnik-2) was studied using numerical simulation. The influence of the flow geometry on scalar shear stresses (SSS), the residence time, and the volume of recirculation zones was determined. Volume fractions of SSS were obtained for the threshold stress levels of 9, 50, and 150 Pa at a fixed pump speed of 8000 rpm (mean flow rate, 4.5 L/min; pressure, 80 mm Hg). At all selected threshold stress levels, the elevated SSS volumes for the first-generation rotor pump were found to exceed those for the second-generation pump. Thus, the latter has a lesser effect on blood cells. The average residence time was found to be 39 and 29 ms for the Sputnik-1 and Sputnik-2 pumps, respectively; the respective recirculation zone volumes were 4.36 and 1.72 mL. The lesser volume of recirculation zones for the second-generation rotor pump reduces the probability of formation of stagnation zones and, therefore, the probability of clotting. The simulation results showed that upgrading the design of the Sputnik rotor pump had a positive effect on its hemocompatibility.

This is a preview of subscription content, access via your institution.


  1. 1.

    Mendis, Sh., Puska, P., and Norrving, B., Global Atlas on h Organization, World Heart Federation, World Stroke Organization (2011).

  2. 2.

    Miller, L. W., Guglin, M., and Rogers, J., “Cost of ventricular assist devices: Can we afford the progress?” Circulation, 127, No. 6, 743-748 (2013).

    Article  Google Scholar 

  3. 3.

    Mulloy, D. P., Bhamidipati, C. M., Stone, M. L., Ailawadi, G., Kron, I. L., and Kern, J. A., “Orthotopic heart transplant versus left ventricular assist device: A national comparison of cost and survival,” J. Thor. Cardiovasc. Surg., 145, No. 2, 566-574 (2013).

    Article  Google Scholar 

  4. 4.

    Petukhov, D. S., Selishchev, S. V., and Telyshev, D. V., “Development of left ventricular assist devices as the most effective acute heart failure therapy,” Biomed. Eng., 48, No. 6, 328-330 (2015).

    Article  Google Scholar 

  5. 5.

    Selishchev, S. V. and Telyshev, D. V., “Optimisation of the Sputnik-VAD design,” Int. J. Artif. Org., 39, No. 8, 407-414 (2016).

    Article  Google Scholar 

  6. 6.

    Telyshev, D. V., Denisov, M. V., and Selishchev, S. V., “The effect of rotor geometry on the H−Q curves of the Sputnik implantable pediatric rotary blood pump,” Biomed. Eng., 50, No. 6, 420-424 (2017).

    Article  Google Scholar 

  7. 7.

    Denisov, M. V., Selishchev, S. V., Telyshev, D. V., and Frolova, E. A., “Development of medical and technical requirements and simulation of the flow–pressure characteristics of the Sputnik pediatric rotary blood pump,” Biomed. Eng., 50, No. 5, 296-299 (2017).

    Article  Google Scholar 

  8. 8.

    Telyshev, D. V., Denisov, M. V., Pugovkin, A., Selishchev, S. V., and Nesterenko, I. V., “The progress in the novel pediatric rotary blood pump Sputnik development,” Artif. Organs, 42, No. 4, 432-443 (2018).

    Article  Google Scholar 

  9. 9.

    Lopes, G. Jr., Bock, E., and Gomez, L., “Numerical analyses for low Reynolds flow in a ventricular assist device low Reynolds flow in a ventricular assist device,” Artif. Org., 41, No. 6, 30-40 (2017).

    Article  Google Scholar 

  10. 10.

    Sohrabi, S. and Liu, Y., “A cellular model of shear-induced hemolysis,” Artif. Org., 41, No. 9, 1-12 (2017).

    Article  Google Scholar 

  11. 11.

    Versteeg, H. K. and Malalasekera, W., An Introduction to Computational Fluid Dynamics: The Finite Volume Method, Harlow, Pearson Education Limited (2007).

  12. 12.

    Bludszuweit, C., “Three-dimensional numerical prediction of stress loading of blood particles in a centrifugal pump,” Artif. Org., 19, No. 7, 590-596 (1995).

    Article  Google Scholar 

  13. 13.

    Science Clarified: Blood, AdvaMeg (2007), pp. 50-56.

  14. 14.

    Giersiepen, M., Wurzinger, L. J., Opitz, R., and Reul, H., “Estimation of shear stress-related blood damage in heart valve prosthesis − in vitro comparison of 25 aortic valves,” Int. J. Artif. Org., 13, 300-306 (1990).

    Article  Google Scholar 

  15. 15.

    Hochareon, P., Manning, K. B., Fontaine, A. A., Tarbell, J. M., and Deutsch, S., “Correlation of in vivo clot deposition with the flow characteristics in the 50 cc Penn State artificial heart: A preliminary study,” ASAIO J., 50, No. 6, 537-542 (2004).

    Article  Google Scholar 

  16. 16.

    Fraser, K. H., Zhang, T., Taskin, M. E., Griffith, B. P., and Wu, Z. J., “Computational fluid dynamics analysis of thrombosis potential in ventricular assist device drainage cannulae,” ASAIO J., 56, No. 3, 157-163 (2010).

    Article  Google Scholar 

Download references

Author information



Corresponding author

Correspondence to M. V. Denisov.

Additional information

Translated from Meditsinskaya Tekhnika, Vol. 53, No. 3, May-Jun., 2019, pp. 23-25.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Denisov, M.V., Telyshev, D.V., Selishchev, S.V. et al. Investigation of Hemocompatibility of Rotary Blood Pumps: The Case of the Sputnik Ventricular Assist Device. Biomed Eng 53, 181–184 (2019).

Download citation