Biomedical Engineering

, Volume 51, Issue 6, pp 377–380 | Cite as

Chemiresistive Sensors for Thrombin Assay Based on Nanosize Carbon Nanotube Films on Flexible Supports

  • I. A. Komarov
  • E. N. Rubtsova
  • A. S. Lapashina
  • A. V. Golovin
  • I. I. Bobrinetskiy
Theory and Design

We present here results obtained during the developmental construction of a selective biological sensor based on carbon nanotubes chemically modified with specific aptamers. The sensory layer, consisting of a film of carbon nanotubes, on a flexible polymer substrate, provides high sensitivity for assay of the target proteins. The responses of the sensory structures to the target protein − thrombin and a reference protein, albumin − were studied. Selective estimation of thrombin after exposure of the sensor to albumin was demonstrated.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • I. A. Komarov
    • 1
  • E. N. Rubtsova
    • 1
  • A. S. Lapashina
    • 2
  • A. V. Golovin
    • 2
  • I. I. Bobrinetskiy
    • 1
  1. 1.National Research University of Electronic Technology (MIET)MoscowRussia
  2. 2.Faculty of Bioengineering and BioinformaticsM. V. Lomonosov Moscow State UniversityMoscowRussia

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