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Evaluation of Antitumor Efficiency of High Intensity Radiation 169Yb Source on Experimental Sarcoma M-1

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Bulletin of Experimental Biology and Medicine Aims and scope

Rats with sarcoma M-1 were exposed to high dose rate irradiation with 169Yb source. In 25 days after introduction of a trocar with sealed capsule with 169Yb source into the tumor, complete tumor regression was observed in 70% animals. The results suggest feasibility of using 169Yb source for high-dose rate brachytherapy and development of the personalized medicine approaches.

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Authors and Affiliations

  1. A. F. Tsyb Medical Radiological Research Center, Affiliated Branch of the National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia

    S. E. Ulyanenko, S. N. Koryakin, A. A. Lychagin, M. N. Kuznetsova, V. I. Potetnya, L. N. Ulyanenko & A. I. Brovin

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  1. S. E. Ulyanenko
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  2. S. N. Koryakin
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  3. A. A. Lychagin
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  4. M. N. Kuznetsova
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  5. V. I. Potetnya
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  6. L. N. Ulyanenko
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  7. A. I. Brovin
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Corresponding author

Correspondence to S. N. Koryakin.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 167, No. 1, pp. 91-93, January, 2019

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Ulyanenko, S.E., Koryakin, S.N., Lychagin, A.A. et al. Evaluation of Antitumor Efficiency of High Intensity Radiation 169Yb Source on Experimental Sarcoma M-1. Bull Exp Biol Med 167, 84–86 (2019). https://doi.org/10.1007/s10517-019-04466-4

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  • DOI: https://doi.org/10.1007/s10517-019-04466-4

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