Experimental validation of the method for regulation of stem cell proliferation and differentiation is carried out. The method consists in exposure to ultrahigh frequency electromagnetic radiation, modulated by infralow frequencies with variable parameters. A specially designed programmer, setting up the parameters of exposure, is connected to the source of radiation. The zones of anatomical location of the red bone marrow of rats were exposed for 15 min to the amplitude-modulated electromagnetic radiation of ultrahigh frequency range. The parameters of exposure were determined in previous studies. The red bone marrow was collected from the sternum and head of the femur. The cellular composition of the red bone marrow was evaluated 1, 2, 3, and 6 days after the exposure. The optimal therapeutic mode of irradiation was then chosen, leading to stem cell activation with subsequent proliferation and differentiation into mature red bone marrow cells.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 164, No. 11, pp. 643-645, November, 2017
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Zilov, V.G., Subbotina, T.I., Yashin, A.A. et al. Effects of Electromagnetic Fields Modulated by Infralow Frequencies on the Production of Stem Cells. Bull Exp Biol Med 164, 685–687 (2018). https://doi.org/10.1007/s10517-018-4059-0
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DOI: https://doi.org/10.1007/s10517-018-4059-0