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Experimental Modeling of Alcohol-Induced Liver Cirrhosis in Rats

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Bulletin of Experimental Biology and Medicine Aims and scope

An experimental model of alcohol-induced liver cirrhosis in white outbred rats was developed: intragastric administration of 40% ethanol (3 g/kg) every other day for 3 weeks and simultaneous intraperitoneal administration of 1% of N-nitrozodimethylamine (5 mg/kg) for 4 consecutive days of each week.

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Authors and Affiliations

  1. S. M. Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation, St. Petersburg, Russia

    A. E. Antushevich, A. E. Antushevich, A. N. Grebenyuk, D. A. Khalyutin & A. A. Yartseva

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  1. A. E. Antushevich
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  2. A. E. Antushevich
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  3. A. N. Grebenyuk
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  4. D. A. Khalyutin
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  5. A. A. Yartseva
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Corresponding author

Correspondence to A. E. Antushevich.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 164, No. 9, pp. 393-396, September, 2017

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Antushevich, A.E., Antushevich, A.E., Grebenyuk, A.N. et al. Experimental Modeling of Alcohol-Induced Liver Cirrhosis in Rats. Bull Exp Biol Med 164, 404–407 (2018). https://doi.org/10.1007/s10517-018-4000-6

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  • DOI: https://doi.org/10.1007/s10517-018-4000-6

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