Reversible cerebral ischemia of medium severity was reproduced in male Wistar rats by bilateral occlusion of the common carotid arteries. Solid-phase structures (anisomorphons) were obtained by marginal dehydration of the serum. Small focal isotropic defects in the serum anisomorphon texture were found in 100% cases during occlusion of the carotid arteries. Similar signs were detected in all patients with chronic cerebral ischemia, which proved specificity of this morphological marker of the disease.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 164, No. 9, pp. 351-355, September, 2017
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Shatokhina, S.N., Aleksandrin, V.V., Shatokhina, I.S. et al. A Marker of Cerebral Ischemia in Solid State Structures of Blood Serum. Bull Exp Biol Med 164, 366–370 (2018). https://doi.org/10.1007/s10517-018-3991-3
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DOI: https://doi.org/10.1007/s10517-018-3991-3