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Bulletin of Experimental Biology and Medicine

, Volume 162, Issue 4, pp 510–514 | Cite as

Structural Reorganization of the Vaginal Mucosa in Stress Urinary Incontinence under Conditions of Er:YAG Laser Treatment

Article

Structural characteristics of the vaginal mucosa in stress incontinence and its correction by IncontiLase technology were studied. Studies of vaginal biopsy specimens before the exposure showed degenerative and atrophic changes in the stratified squamous epithelium, disorganization of fibrillar structures of the intercellular matrix, and microcirculatory disorders. Studies after Er:YAG laser exposure showed signs of neocollagenogenesis and elastogenesis, foci of neoangiogenesis, reduction of epithelial degeneration and atrophy, and an increase of the fibroblast population. Morphometry showed that the volume density of blood capillaries and the thickness of the epithelial layer increased by 61.1 and 64.5%, respectively. The use of IncontiLase technology in stress incontinence led to structural reorganization of the vaginal mucosa, improving its morphology and function and alleviating the symptoms of incontinence.

Key Words

stress urinary incontinence IncontiLase Laser technology Er:YAG laser vaginal biopsy morphometry 

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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  • G. A. Lapii
    • 1
  • A. Yu. Yakovleva
    • 1
  • A. I. Neimark
    • 2
  1. 1.Institute of Molecular Pathology and PathomorphologyNovosibirskRussia
  2. 2.Altai State Medical UniversityBarnaulRussia

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