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Analgesic Effect of Xenon in Rat Model of Inflammatory Pain

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Bulletin of Experimental Biology and Medicine Aims and scope

The analgesic effects of inert gas xenon were examined on rats. The formalin model of inflammatory pain, tail-flick test, and hot-plate test revealed the antinociceptive effects of subanesthetizing doses of inhalation anesthetic xenon. Inhalation of 50/50 xenon/oxygen mixture moderated the nociceptive responses during acute and tonic phases of inflammatory pain.

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Authors and Affiliations

  1. Research Institute of General Pathology and Pathological Physiology, Moscow, Russia

    M. L. Kukushkin, S. I. Igon’kina, S. V. Potapov & A. V. Potapov

  2. I. M. Sechenov First Moscow State Medical University, Moscow, Russia

    M. L. Kukushkin

Authors
  1. M. L. Kukushkin
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  2. S. I. Igon’kina
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  3. S. V. Potapov
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  4. A. V. Potapov
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Corresponding author

Correspondence to M. L. Kukushkin.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 162, No. 10, pp. 445-447, October, 2016

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Kukushkin, M.L., Igon’kina, S.I., Potapov, S.V. et al. Analgesic Effect of Xenon in Rat Model of Inflammatory Pain. Bull Exp Biol Med 162, 451–453 (2017). https://doi.org/10.1007/s10517-017-3637-x

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  • DOI: https://doi.org/10.1007/s10517-017-3637-x

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