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Antiulcer Activity of Extracts of Ecdysteroid-Containing Plants of Genera Lychnis and Silene of the Caryophyllaceae Family

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We studied antiulcer activity of the extracts of ecdysteroid-containing plants of the Caryophyllaceae family: Lychnis chalcedonica L., Silene viridiflora L.Sp.Pl., and Silene frivaldszkyana Hampe. Experiments on the model of neurogenic and aspirin-induced ulcerogenesis showed unidirectional and pronounced gastroprotective effects of S. viridiflora and L. chalcedonica extracts comparable to the efficacy of famotidine. In these models, a course of intragastric treatment with the extracts reduced ulcerative lesions of all types.

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References

  1. L. I. Alekseeeva, E. N. Anufrieva, V. V. Volodin, et al., Phytoecdysteroids [in Russian], St. Petersburg (2003), 2003.

  2. Yu. K. Gusak, V. N. Darmograi, Yu. V. Karaseva, et al., Vest. Nov. Med. Tekhn., No. 3, 64-67 (2002).

  3. L. N. Zibareva, Phytoecdysteroids of Plants of the Family Caryophyllaceae [in Russian], Saarbruecken (2012).

  4. E. P. Zueva, D. V. Reikhart, S. G. Krylova, et al., Medicinal Plants in The Treatment Of Gastric and Duodenal Ulcer [in Russian], Tomsk (2003).

  5. A. I. Orlov, Econometrics [in Russian], Rostov-on-Don (2009).

  6. M. B. Plotnikov, O. I. Aliev, A. S. Vasiliev, et al., Bull. Exp. Biol. Med., 139, No. 1, 60-63 (2005).

    Article  CAS  PubMed  Google Scholar 

  7. Manual of Preclinical Studies of New Drugs, Part I, Ed. A. N. Mironov [in Russian], Moscow (2012).

  8. Ya. S. Zimmerman, Manual on Gastroenterology [in Russian], Moscow (2012).

  9. A. V. Shishkina, Farmatsiya, No. 1, 28-30 (2013).

  10. L. Dinan and R. Lafont, J. Endocrinol., 191, No. 1, 1-8 (2006).

    Article  CAS  PubMed  Google Scholar 

  11. N. Mamadalieva, L. Zibareva, N. Evrard-Todeschi, et al., Collect. Czech. Chem. Commun., 69, No. 8, 1675-1680 (2004).

    Article  CAS  Google Scholar 

  12. L. Zibareva, Arch. Insect Biochem. Physiol., 43, No. 1, 1-8 (2000).

    Article  CAS  PubMed  Google Scholar 

  13. L. Zibareva, V. I. Yeriomina, N. Munkhjargal, et al., Arch. Insect Biochem. Physiol., 72, No. 4, 234-248 (2009).

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia

    S. G. Krylova, E. P. Zueva, E. N. Amosova & T. G. Razina

  2. National Research Tomsk State University, Tomsk, Russia

    L. N. Zibareva

Authors
  1. S. G. Krylova
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  2. E. P. Zueva
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  3. L. N. Zibareva
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  4. E. N. Amosova
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  5. T. G. Razina
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Corresponding author

Correspondence to S. G. Krylova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 158, No. 8, pp. 190-194, August, 2014

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Krylova, S.G., Zueva, E.P., Zibareva, L.N. et al. Antiulcer Activity of Extracts of Ecdysteroid-Containing Plants of Genera Lychnis and Silene of the Caryophyllaceae Family. Bull Exp Biol Med 158, 225–228 (2014). https://doi.org/10.1007/s10517-014-2728-1

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  • DOI: https://doi.org/10.1007/s10517-014-2728-1

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