Abstract
To derive a method of identifying use of evidence-based psychotherapy (EBP) for post-traumatic stress disorder (PTSD), we used clinical note text from national Veterans Health Administration (VHA) medical records. Using natural language processing, we developed machine-learning algorithms to classify note text on a large scale in an observational study of Iraq and Afghanistan veterans with PTSD and one post-deployment psychotherapy visit by 8/5/15 (N = 255,968). PTSD visits were linked to 8.1 million psychotherapy notes. Annotators labeled 3467 randomly-selected psychotherapy notes (kappa = 0.88) to indicate receipt of EBP. We met our performance targets of overall classification accuracy (0.92); 20.2% of veterans received ≥ one session of EBP over the study period. Our method can assist with identifying EBP use and studying EBP-associated outcomes in routine clinical practice.
References
Baharudin, B., Lee, L. H., & Khan, K. A. (2010). Review of machine learning algorithms for text-documents classification. Journal of Advances in Information Technology, 1(1), 4–20. https://doi.org/10.4304/jait.1.1.4-20.
Batuwita, R., & Palade, V. (2013). Class imbalance learning methods for support vector machines. In Imbalanced learning (pp. 83–99). Hoboken, NJ: Wiley.
Chang, C. C., & Lin, C. J. (2011). LIBSVM: A library for support vector machines. ACM Transactions on Intelligent Systems and Technology, 2(3), 1–27. https://doi.org/10.1145/1961189.1961199.
Chard, K. M., Schumm, J. A., Owens, G. P., & Cottingham, S. M. (2010). A comparison of OEF and OIF veterans and Vietnam veterans receiving cognitive processing therapy. Journal of Traumatic Stress, 23(1), 25–32. https://doi.org/10.1002/jts.20500.
Cornia, R., Patterson, O. V., Ginter, T., & DuVall, S. L. (2014). Rapid NLP development with Leo. In AMIA Annual Symposium Proceedings. (p. 1356).
Cully, J. A., Tolpin, L., Henderson, L., Jimenez, D., Kunik, M. E., & Peterson, L. A. (2008). Psychotherapy in the Veterans Health Administration: Missed opportunities?. Psychological Services, 5(4), 320–331. https://doi.org/10.1037/a0013719.
D’Avolio, L. W., Nguyen, T. M., Farwell, W. R., Chen, Y., Fitzmeyer, F., Harris, O. M., & Fiore, L. D. (2010). Evaluation of a generalizable approach to clinical information retrieval using the automated retrieval console (ARC). Journal of the American Medical Informatics Association, 17(4), 375–382. https://doi.org/10.1136/jamia.2009.001412.
Dreyer, N. A., Tunis, S. R., Berger, M., Ollendorf, D., Mattox, P., & Glikich, R. (2010). Why observational studies should be among the tools used in comparative effectiveness research. Health Affairs, 29(10), 1818–1825. https://doi.org/10.1377/hlthaff.2010.0666.
Ferrucci, D., & Lally, A. (2004). UIMA: An architectural approach to unstructured information processing in the corporate research environment. Natural Language Engineering, 10(3–4), 327–348. https://doi.org/10.1017/S1351324904003523.
Haagen, J. F., Smid, G. E., Knipscheer, J. W., & Kleber, R. J. (2015). The efficacy of recommended treatments for veterans with PTSD: A metaregression analysis. Clinical Psychology Review, 40, 184–194. https://doi.org/10.1016/j.cpr.2015.06.008.
Harpaz-Rotem, I., & Rosenheck, R. A. (2011). Serving those who served: Retention of newly returning veterans from Iraq and Afghanistan in mental health treatment. Psychiatric Services, 62(1), 22–27. https://doi.org/10.1176/ps.62.1.pss6201_0022.
Hebenstreit, C. L., Madden, E., Koo, K. H., & Maguen, S. (2015). Minimally adequate mental health care and latent classes of PTSD symptoms in female Iraq and Afghanistan veterans. Psychiatric Services, 65(12), 1414–1419.
Hsu, C. W., & Lin, C. J. (2002). A comparison of methods for multi-class support vector machines. IEEE Transactions on Neural Networks, 13, 415–425. https://doi.org/10.1109/72.991427.
Karlin, B. E., Ruzek, J. I., Chard, K. M., Eftekhari, A., Monson, C. M., Hembree, E. A., … Foa, E. B. (2010). Dissemination of evidence-based psychological treatments for posttraumatic stress disorder in the veterans health administration. Journal of Traumatic Stress, 23(6), 663–673. https://doi.org/10.1002/jts.20588.
Kehle-Forbes, S. M., Meis, L. A., Spoont, M. R., & Polusny, M. A. (2016). Treatment initiation and dropout from prolonged exposure and cognitive processing therapy in a VA outpatient clinic. Psychological Trauma: Theory, Research, Practice, and Policy, 8(1), 107–114. https://doi.org/10.1037/tra0000065.
Kussman, M. J. (2008). VHA Handbook 1160.01: Uniform mental helath services in VA medical centers and clinic. Accessed March 1, 2010, from http://www1.va.gov/vhapublications/ViewPublication.asp?pub_ID=1762.
Lu, M. W., Plagge, J. M., Marsiglio, M. C., & Dobscha, S. K. (2016). Clinician documentation on receipt of trauma-focused evidence-based psychotherapies in a VA PTSD clinic. Journal of Behavioral Health Services & Research, 43(1), 71–87. https://doi.org/10.1007/s11414-013-9372-9.
Maguen, S., Madden, E., Neylan, T. C., Cohen, B. E., Bertenthal, D., & Seal, K. H. (2014). Timing of mental health treatment and PTSD symptom improvement among Iraq and Afghanistan veterans. Psychiatric Services, 65(12), 1414–1419. https://doi.org/10.1176/appi.ps.201300453
Meystre, S. M., Savova, G. K., Kipper-Schuler, K. C., & Hurdle, J. F. (2008). Extracting information from textual documents in the electronic health record: A review of recent research. Yearbook of Medical Informatics, 35, 128–144.
Monson, C. M., Schnurr, P. P., Resick, P. A., Friedman, M. J., Young-Xu, Y., & Stevens, S. P. (2006). Cognitive processing therapy for veterans with military-related posttraumatic stress disorder. Journal Consulting and Clinical Psychology, 74(5), 898–907. https://doi.org/10.1037/0022-006X.74.5.898.
Mott, J. M., Mondragon, S., Hundt, N. E., Beason-Smith, M., Grady, R. H., & Teng, E. J. (2014). Characteristics of U.S. veterans who begin and complete prolonged exposure and cognitive processing therapy for PTSD. Journal of Traumatic Stress, 27(3), 265–273. https://doi.org/10.1002/jts.21927.
Resick, P. A., Wachen, J. S., Dondanville, K. A., Pruiksma, K. E., Yarvis, J. S., Peterson, A. L., … The STRONG STAR Consortium. (2017). Effect of group vs individual cognitive processing therapy in active-duty military seeking treatment for posttraumatic stress disorder: A randomized clinical trial. JAMA Psychiatry, 74(1), 28–36. https://doi.org/10.1001/jamapsychiatry.2016.2729.
Resick, P. A., Wachen, J. S., Mintz, J., Young-McCaughan, S., Roache, J. D., Borah, A. M., … Peterson, A. L. (2015). A randomized clinical trial of group cognitive processing therapy compared with group present-centered therapy for PTSD among active duty military personnel. Journal of Consulting and Clinical Psychology, 83(6), 1058–1068. https://doi.org/10.1037/ccp0000016.
Rosen, C. S., Eftekhari, A., Crowley, J. J., Smith, B. N., Kuhn, E., Trent, L., … Ruzek, J. I. (2017). Maintenance and reach of exposure psychotherapy for posttraumatic stress disorder 18 months after training. Journal of Traumatic Stress, 30(1), 63–70. https://doi.org/10.1002/jts.22153.
Rosen, C. S., Matthieu, M. M., Stirman, S. W., Cook, J. M., Landes, S., Bernardy, N. C., … Watts, B. V. (2016). A review of studies on the system-wide implementation of evidence-based psychotherapies for posttraumatic stress disorder in the Veterans Health Administration. Administration and Policy in Mental Health and Mental Health Services Research, 43(6), 957–977. https://doi.org/10.1007/s10488-016-0755-0.
Schnurr, P. P., Friedman, M. J., Engel, C. C., Foa, E. B., Shea, M. T., Chow, B. K., … Bernardy, N. (2007). Cognitive behavioral therapy for posttraumatic stress disorder in women: A randomized controlled trial. JAMA Psychaitry, 297(8), 820–830. https://doi.org/10.1001/jama.297.8.820.
Schnurr, P. P., & Lunney, C. A. (2015). Differential effects of prolonged exposure on posttraumatic stress disorder symptoms in female veterans. Journal of Consulting Clinical Psychology, 83(6), 1154–1160. https://doi.org/10.1037/ccp0000031.
Seal, K. H., Bertenthal, D., Miner, C. R., Sen, S., & Marmar, C. (2007). Bringing the war back home: Mental health disorders among 103,788 US veterans returning from Iraq and Afghanistan seen at Department of Veterans Affairs facilities. Archives of Internal Medicine, 167(5), 476–482. https://doi.org/10.1001/archinte.167.5.476.
Seal, K. H., Maguen, S., Bertenthal, D., Batki, S. L., Striebel, J., Stein, M. B., Madden, E., & Neylan, T. C. (2016). Observational evidence for buprenorphine’s impact on posttraumatic stress symptoms in Veterans with chronic pain and opioid use disorder. Journal of Clinical Psychiatry, 77(9), 1182–1188. https://doi.org/10.4088/JCP.15m09893.
Seal, K. H., Maguen, S., Cohen, B., Gima, K. S., Metzler, T. J., Ren, L., … Marmar, C. R. (2010). VA mental health services utilization in Iraq and Afghanistan veterans in the first year of receiving new mental health diagnoses. Journal of Traumatic Stress, 23(1), 5–16. https://doi.org/10.1002/jts.20493.
Shiner, B., D’Avolio, L. W., Nguyen, T. M., Zayed, M. H., Young-Xu, Y., Desai, R. A., … Watts, B. V. (2013). Measuring use of evidence based psychotherapy for posttraumatic stress disorder. Administration and Policy in Mental Health and Mental Health Services Research, 40(4), 311–318. https://doi.org/10.1007/s10488-012-0421-0.
Shiner, B., D’Avolio, L. W., Nguyen, T. N., Zayed, M. H., Watts, B. V., & Fiore, L. (2012). Automated classification of psychotherapy note text: Implications for quality assessment in PTSD care. Journal of Evaluation in Clinical Practice, 18(3), 698–701. https://doi.org/10.1111/j.1365-2753.2011.01634.x.
Shiner, B., Westgate, C. L., Bernary, N. C., Schnurr, P. P., & Watts, B. V. (2017). Anticonvulsant medication use in veterans with posttraumatic stress disorder. Journal of Clinical Psychiatry, 78(5), e545–e552. https://doi.org/10.4088/JCP.16m11031.
Shiner, B., Westgate, C. L., Simiola, V., Thompson, R., Schnurr, P. P., & Cook, J. M. Measuring use of evidence-based psychotherapy for PTSD in VA residential treatment settings with clinician survey and electronic medical record templates. Military Medicine (in press).
Smith, E. R., Porter, K. E., Messina, M. G., Beyer, J. A., Defever, M. E., Foa, E. B., & Rauch, S. A. (2015). Prolonged exposure for PTSD in a Veteran group: A pilot effectiveness study. Journal of Anxiety Disorders, 30, 23–27. https://doi.org/10.1016/j.janxdis.2014.12.008.
Spoont, M. R., Murdoch, M., Hodges, J., & Nugent, S. (2010). Treatment receipt by veterans after a PTSD diagnosis in PTSD, mental health, or general medical clinics. Psychiatric Services, 61(1), 58–63. https://doi.org/10.1176/ps.2010.61.1.58.
Tuerk, P. W., Yoder, M., Grubaugh, A., Myrick, H., Hamner, M., & Acierno, R. (2011). Prolonged exposure therapy for combat-related posttraumatic stress disorder: An examination of treatment effectiveness for veterans of the wars in Afghanistan and Iraq. Journal of Anxiety Disorders, 25(3), 397–403. https://doi.org/10.1016/j.janxdis.2010.11.002.
Voelkel, E., Pukay-Martin, N. D., Walter, K. H., & Chard, K. M. (2015). Effectiveness of cognitive processing therapy for male and female U.S. Veterans with and without military sexual trauma. Journal of Traumatic Stress, 28(3), 174–182. https://doi.org/10.1002/jts.22006.
Yoder, M., Tuerk, P. W., Price, M., Grubaugh, A. L., Strachan, M., Myrick, H., & Acierno, R. (2012). Prolonged exposure therapy for combat-related posttraumatic stress disorder: Comparing outcomes for Veterans of different wars. Psychological Services, 9(1), 16–25. https://doi.org/10.1037/a0026279.
Zubkoff, L., Carpenter-Song, E., Shiner, B., Ronconi, J. M., & Watts, B. V. (2016). Clinicians’ perception of patient readiness for treatment: An emerging theme in implementation science. Administration and Policy in Mental Health and Mental Health Services Research, 43(2), 250–258. https://doi.org/10.1007/s10488-015-0635-z.
Acknowledgements
We would like to thank Corinne Halls and the VINCI services clinical annotation team for performing manual chart review. We would also like to thank Callan Lujan for her assistance with this manuscript.
Funding
This work was funded by Department of Defense Grant W81XWH-15-1-0038 (Maguen) and VA grant HSR&D CDA11-263 (Shiner).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Appendices
Appendix 1
See Table 4.
Appendix 2
See Table 5.
Appendix 3: CPT and PE Guidelines for Annotation
Cognitive Processing Therapy (CPT)—Individual Therapy
-
If the title or body of the note states “CPT Session #n”, and is an individual session, consider it CPT—individual.
-
Examples of CPT notes:
-
“Content: this was the fifth session of cognitive processing therapy (CPT) for PTSD.”
-
“Cognitive processing therapy: initial session.”
-
-
-
Not to be confused with CBT (cognitive behavioral therapy) or with CPT (current procedural terminology) code sets. If numbers follow the initials CPT, it is likely referring to a CPT code.
Cognitive processing therapy (CPT) is a cognitive-behavioral therapy for PTSD and related conditions. CPT typically consists of 12, 50-min therapy sessions. CPT utilizes trauma-specific cognitive challenging techniques to help patients move past inaccurate negative thoughts (called “stuck points”) and progress toward recovery. Additionally, this therapy can be conducted with or without a written trauma account and in individual or group formats.
-
Additional phrases in the body of the text may identify a CPT session:
-
Safety module
-
Impact statement
-
Trust module
-
Intimacy module
-
Esteem module
-
Power/control module
-
Trauma account
-
Stuck point(s)
-
Challenging questions
-
Patterns of problematic thinking
-
Socratic questioning
-
Final impact statement
-
Cognitive Processing Therapy (CPT)—Group Therapy
-
If the title or body of the note states “CPT Session #n”, and is a group session, consider it CPT—group therapy.
-
Same criteria as listed in CPT-individual above, but note is clearly referring to a CPT group therapy session.
Prolonged Exposure (PE)—Individual Therapy
The goal of prolonged exposure therapy is to promote processing of the trauma memory and to reduce distress and avoidance evoked by the trauma reminders. The imaginal exposure typically occurs during the therapy session and consists of retelling the trauma to the therapist. For the in vivo exposure, the clinician works with the client to establish a fear and avoidance hierarchy and typically assigns exposures to these list items as homework progressively. Both components work by facilitating emotional processing so that the problematic traumatic memories and avoidances habituate (desensitize).
-
To address the traumatic memories and triggers that are reminders of the trauma, the core components of prolonged exposure therapy are:
-
1.
Imaginal exposure, revisiting the traumatic memory, repeated recounting it aloud, and processing the revisiting experience, and
-
2.
in vivo exposure, the repeated confrontation with situations and objects that cause distress but are not inherently dangerous.
-
3.
Additional phrases found in the body of the text may identify a PE session:
-
In vivo hierarchy
-
Hot spots
-
-
1.
-
Examples of PE notes:
-
Prolonged exposure imaginal sessions.
-
Time in session (in minutes): 90.
-
Session Number: 5.
-
-
If the title or body of the note says “PE Session #n”, and is an individual session, consider it PE-individual therapy.
-
Check the note’s content carefully to make sure PE does not refer to “physical exam” or “pulmonary embolism”.
Prolonged Exposure (PE)—Group Therapy (Combined with Individual)
If the title or body of the note says “PE Session #n”, and is a group session, consider it PE-group therapy.
Same criteria as listed in PE-individual therapy above, but note is clearly referring to a PE-group therapy session.
Do not annotate as PE unless it is clearly only PE and not combined with DBT or some other modality. Only capture PE group for notes that indicate both imaginal and in vivo components were present, and another modality was not be used concurrently.
Rights and permissions
About this article
Cite this article
Maguen, S., Madden, E., Patterson, O.V. et al. Measuring Use of Evidence Based Psychotherapy for Posttraumatic Stress Disorder in a Large National Healthcare System. Adm Policy Ment Health 45, 519–529 (2018). https://doi.org/10.1007/s10488-018-0850-5
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10488-018-0850-5