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Applied Mathematics and Mechanics

, Volume 37, Issue 12, pp 1631–1646 | Cite as

Numerical simulation of magnetic drug targeting with Eulerian-Lagrangian model and effect of viscosity modification due to diabetics

  • M. M. Larimi
  • A. RamiarEmail author
  • A. A. Ranjbar
Article

Abstract

The targeted drug delivery and targeted drug therapy transport a drug directly to the center of the disease under various conditions and thereby treat it deliberately without effects on the body. This paper studies the magnetic drug targeting (MDT) technique by particle tracking in the presence of magnetic field in bifurcation vessels of a healthy person and a diabetes patient. The Lagrangian particle tracking is performed to estimate particle behavior under effects of imposed magnetic field gradients along the bifurcation. The results show that the magnetic field increases the volume fraction of particle in the target region, and the efficiency of MDT on a patient with the diabetes disease is better than a healthy person. Also, for the higher magnetic numbers, the flow in the upper branch is strongly affected by the magnetic field.

Key words

bifurcation particle tracking Lagrangian method magnetic nano-particles 

Chinese Library Classification

O35 

2010 Mathematics Subject Classification

76D05 

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Copyright information

© Shanghai University and Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  1. 1.Faculty of Mechanical EngineeringBabol Noshirvani University of TechnologyBabolIran

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